Context Theory and simulation suggest that randomized controlled trials (RCTs) stopped early for benefit (truncated RCTs) systematically overestimate treatment effects for the …
BR Haight, SM Learned, CM Laffont, PJ Fudala, Y Zhao… - The Lancet, 2019 - thelancet.com
Background RBP-6000, referred to as BUP-XR (extended-release buprenorphine), is a subcutaneously injected, monthly buprenorphine treatment for opioid use disorder. BUP-XR …
Importance Buprenorphine opioid agonist treatment (OAT) has established efficacy for treating opioid dependency among persons seeking addiction treatment. However …
World Health Organization. Department of Mental … - 2009 - books.google.com
These Guidelinesreview the use of medicines such as methadone, buprenorphine, naltrexone and clonidine in combination with psychosocial support in the treatment of …
L Amato, M Davoli, CA Perucci, M Ferri… - Journal of substance …, 2005 - Elsevier
AIM: To summarize the major findings of the five Cochrane reviews on substitution maintenance treatments for opioid dependence. METHODS: We conducted a narrative and …
PJ Fudala, TP Bridge, S Herbert… - … England Journal of …, 2003 - Mass Medical Soc
Background Office-based treatment of opiate addiction with a sublingual-tablet formulation of buprenorphine and naloxone has been proposed, but its efficacy and safety have not …
J Kakko, KD Svanborg, MJ Kreek, M Heilig - The Lancet, 2003 - thelancet.com
Background The partial opiate-receptor agonist buprenorphine has been suggested for treatment of heroin dependence, but there are few long-term and placebo-controlled studies …
CP Thomas, CA Fullerton, M Kim… - Psychiatric …, 2014 - Am Psychiatric Assoc
Objective Buprenorphine maintenance treatment (BMT) and methadone maintenance treatment (MMT) are pharmacological treatment programs for individuals with opioid use …
A Elkader, B Sproule - Clinical pharmacokinetics, 2005 - Springer
Buprenorphine is a semi-synthetic opioid derived from thebaine, a naturally occurring alkaloid of the opium poppy, Papaver somniferum. The pharmacology of buprenorphine is …