Buprenorphine maintenance versus placebo or methadone maintenance for opioid dependence

RP Mattick, C Breen, J Kimber… - Cochrane database of …, 2014 - cochranelibrary.com
Background Buprenorphine maintenance treatment has been evaluated in randomised
controlled trials against placebo medication, and separately as an alternative to methadone …

Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis

D Bassler, M Briel, VM Montori, M Lane, P Glasziou… - Jama, 2010 - jamanetwork.com
Context Theory and simulation suggest that randomized controlled trials (RCTs) stopped
early for benefit (truncated RCTs) systematically overestimate treatment effects for the …

Efficacy and safety of a monthly buprenorphine depot injection for opioid use disorder: a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial

BR Haight, SM Learned, CM Laffont, PJ Fudala, Y Zhao… - The Lancet, 2019 - thelancet.com
Background RBP-6000, referred to as BUP-XR (extended-release buprenorphine), is a
subcutaneously injected, monthly buprenorphine treatment for opioid use disorder. BUP-XR …

Buprenorphine treatment for hospitalized, opioid-dependent patients: a randomized clinical trial

JM Liebschutz, D Crooks, D Herman… - JAMA internal …, 2014 - jamanetwork.com
Importance Buprenorphine opioid agonist treatment (OAT) has established efficacy for
treating opioid dependency among persons seeking addiction treatment. However …

[图书][B] Guidelines for the psychosocially assisted pharmacological treatment of opioid dependence

World Health Organization. Department of Mental … - 2009 - books.google.com
These Guidelinesreview the use of medicines such as methadone, buprenorphine,
naltrexone and clonidine in combination with psychosocial support in the treatment of …

An overview of systematic reviews of the effectiveness of opiate maintenance therapies: available evidence to inform clinical practice and research

L Amato, M Davoli, CA Perucci, M Ferri… - Journal of substance …, 2005 - Elsevier
AIM: To summarize the major findings of the five Cochrane reviews on substitution
maintenance treatments for opioid dependence. METHODS: We conducted a narrative and …

Office-based treatment of opiate addiction with a sublingual-tablet formulation of buprenorphine and naloxone

PJ Fudala, TP Bridge, S Herbert… - … England Journal of …, 2003 - Mass Medical Soc
Background Office-based treatment of opiate addiction with a sublingual-tablet formulation
of buprenorphine and naloxone has been proposed, but its efficacy and safety have not …

1-year retention and social function after buprenorphine-assisted relapse prevention treatment for heroin dependence in Sweden: a randomised, placebo-controlled …

J Kakko, KD Svanborg, MJ Kreek, M Heilig - The Lancet, 2003 - thelancet.com
Background The partial opiate-receptor agonist buprenorphine has been suggested for
treatment of heroin dependence, but there are few long-term and placebo-controlled studies …

Medication-assisted treatment with buprenorphine: assessing the evidence

CP Thomas, CA Fullerton, M Kim… - Psychiatric …, 2014 - Am Psychiatric Assoc
Objective Buprenorphine maintenance treatment (BMT) and methadone maintenance
treatment (MMT) are pharmacological treatment programs for individuals with opioid use …

Buprenorphine: clinical pharmacokinetics in the treatment of opioid dependence

A Elkader, B Sproule - Clinical pharmacokinetics, 2005 - Springer
Buprenorphine is a semi-synthetic opioid derived from thebaine, a naturally occurring
alkaloid of the opium poppy, Papaver somniferum. The pharmacology of buprenorphine is …