Combination therapies for biofilm inhibition and eradication: a comparative review of laboratory and preclinical studies

S Hawas, AD Verderosa, M Totsika - Frontiers in cellular and infection …, 2022 - frontiersin.org
Microbial biofilms are becoming increasingly difficult to treat in the medical setting due to
their intrinsic resistance to antibiotics. To combat this, several biofilm dispersal agents are …

Pathogen–Host Interactions in Pseudomonas aeruginosa Pneumonia

RT Sadikot, TS Blackwell, JW Christman… - American journal of …, 2005 - atsjournals.org
Pseudomonas aeruginosa is an important pathogen causing a wide range of acute and
chronic infections. P. aeruginosa rarely causes infection in the normal host, but is an efficient …

Mechanisms of bacterial inactivation in the liquid phase induced by a remote RF cold atmospheric pressure plasma jet

CAJ Van Gils, S Hofmann, B Boekema… - Journal of Physics D …, 2013 - iopscience.iop.org
A radio-frequency atmospheric pressure argon plasma jet is used for the inactivation of
bacteria (Pseudomonas aeruginosa) in solutions. The source is characterized by …

Nitric oxide: a key mediator of biofilm dispersal with applications in infectious diseases

N Barraud, M J. Kelso, S A. Rice… - Current pharmaceutical …, 2015 - benthamdirect.com
Studies of the biofilm life cycle can identify novel targets and strategies for improving biofilm
control measures. Of particular interest are dispersal events, where a subpopulation of cells …

[HTML][HTML] Role of cold atmospheric plasma in microbial inactivation and the factors affecting its efficacy

S Das, VP Gajula, S Mohapatra, G Singh, S Kar - Health Sciences Review, 2022 - Elsevier
The rise in multidrug-resistant pathogens and biofilms has become a significant issue to
address. In the rise of the hour, various innovating technologies are being used to combat …

Pseudomonas aeruginosa: Host defence in lung diseases

BJ Williams, J Dehnbostel, TS Blackwell - Respirology, 2010 - Wiley Online Library
Lung infections caused by the opportunistic pathogen Pseudomonas aeruginosa can
present as a spectrum of clinical entities from a rapidly fatal pneumonia in a neutropenic …

[HTML][HTML] Innate immune responses to Pseudomonas aeruginosa infection

EG Lavoie, T Wangdi, BI Kazmierczak - Microbes and infection, 2011 - Elsevier
Innate immune responses play a critical role in controlling acute infections due to
Pseudomonas aeruginosa in both mice and in humans. In this review we focus on innate …

Nitric oxide: clinical applications in critically ill patients

S Redaelli, A Magliocca, R Malhotra, G Ristagno… - Nitric Oxide, 2022 - Elsevier
Inhaled nitric oxide (iNO) acts as a selective pulmonary vasodilator and it is currently
approved by the FDA for the treatment of persistent pulmonary hypertension of the newborn …

[HTML][HTML] Antimicrobial effects of nitric oxide in murine models of Klebsiella pneumonia

SB Wiegand, L Traeger, HK Nguyen, KR Rouillard… - Redox biology, 2021 - Elsevier
Rationale Inhalation of nitric oxide (NO) exerts selective pulmonary vasodilation. Nitric oxide
also has an antimicrobial effect on a broad spectrum of pathogenic viruses, bacteria and …

Cryptococcus gattii isolates from the British Columbia cryptococcosis outbreak induce less protective inflammation in a murine model of infection than Cryptococcus …

PY Cheng, A Sham, JW Kronstad - Infection and immunity, 2009 - Am Soc Microbiol
The fungal pathogen Cryptococcus neoformans causes approximately one million cases of
cryptococcosis per year in people with AIDS. In contrast, the related species C. gattii is …