Humans and animals are repeatedly exposed to endocrine disruptors, many of which are
ubiquitous in the environment. Endocrine disruptors interfere with hormone action; thus …

Abstract Gulf War Illness (GWI), a chronic multisymptom health problem, afflicts~ 30% of
veterans served in the first GW. Impaired brain function is among the most significant …

The mechanistic target of rapamycin complex 1 (mTORC1) regulates metabolism and cell
growth in response to nutrient, growth, and oncogenic signals. We found that mTORC1 …

Background: DNA methylation is a form of epigenetic modification that has been shown to
play a significant role in gene regulation. In cancer, DNA methylation plays an important role …

Abstract Background Prostate cancer (PCa) has the highest incidence rates of cancers in
men in western countries. Unlike several other types of cancer, PCa has few genetic drivers …

In this review, advances in the understanding of epigenetic reprogramming from fertilization
to the development of primordial germline cells in a mouse and human embryo are …

DNA methylation is a fundamental epigenetic modification in the human genome; pivotal in
development, genomic imprinting, X inactivation, chromosome stability, gene expression …

Irrespective of sex and age, cancer is the leading cause of mortality around the globe.
Therapeutic incompliance, unwanted effects, and economic burdens imparted by cancer …

Sequencing technologies have changed not only our approaches to classical genetics, but
also the field of epigenetics. Specific methods allow scientists to identify novel genome-wide …

Hydrogen sulfide (H 2 S) is a novel gasotransmitter produced endogenously in mammalian
cells, which works by mediating diverse physiological functions. An imbalance in H 2 S …