Recent advances in the discovery of nicotinic acetylcholine receptor allosteric modulators

D Manetti, S Dei, HR Arias, L Braconi, A Gabellini… - Molecules, 2023 - mdpi.com
Positive allosteric modulators (PAMs), negative allosteric modulators (NAMs), silent
agonists, allosteric activating PAMs and neutral or silent allosteric modulators are …

[HTML][HTML] Advances in small molecule selective ligands for heteromeric nicotinic acetylcholine receptors

C Matera, C Papotto, C Dallanoce… - Pharmacological Research, 2023 - Elsevier
The study of nicotinic acetylcholine receptors (nAChRs) has significantly progressed in the
last decade, due to a) the improved techniques available for structural studies; b) the …

L-theanine attenuates nicotine reward and withdrawal signs in mice

Y Alkhlaif, M El-Halawany, W Toma, A Park… - Neuroscience …, 2023 - Elsevier
Abstract Background L-theanine, 2-amino-4-(ethylcarbamoyl) butyric acid, an amino acid
detected in green tea leaves, is used as a dietary supplement to attenuate stress and …

Membrane Hormone Receptors and Their Signaling Pathways as Targets for Endocrine Disruptors

Y Combarnous, TMD Nguyen - Journal of Xenobiotics, 2022 - mdpi.com
The endocrine disruptors are mostly small organic molecules developed for numerous and
very diverse industrial applications. They essentially act through nuclear receptors with …