RDP4: Detection and analysis of recombination patterns in virus genomes

DP Martin, B Murrell, M Golden, A Khoosal… - Virus …, 2015 - academic.oup.com
RDP4 is the latest version of recombination detection program (RDP), a Windows computer
program that implements an extensive array of methods for detecting and visualising …

Notes on recombination and reassortment in multipartite/segmented viruses

A Varsani, P Lefeuvre, P Roumagnac… - Current opinion in virology, 2018 - Elsevier
Highlights•Multipartite and segmented viruses are members of∼ 11% of classified virus
genera.•Segmented viruses with semi-infectious particles have higher propensity to …

A trait-based approach to predicting viral host-range evolvability

HM Strobel, EC Stuart, JR Meyer - Annual Review of Virology, 2022 - annualreviews.org
Predicting the evolution of virus host range has proven to be extremely difficult, in part
because of the sheer diversity of viruses, each with unique biology and ecological …

Paucity of intact non-induced provirus with early, long-term antiretroviral therapy of perinatal HIV infection

K Rainwater-Lovett, C Ziemniak, D Watson… - PLoS …, 2017 - journals.plos.org
The latent reservoir is a major barrier to HIV eradication. Reservoir size is emerging as an
important biomarker to assess the likelihood of HIV remission in the absence of antiretroviral …

Pervasive and non-random recombination in near full-length HIV genomes from Uganda

HE Grant, EB Hodcroft, D Ssemwanga… - Virus …, 2020 - academic.oup.com
Recombination is an important feature of HIV evolution, occurring both within and between
the major branches of diversity (subtypes). The Ugandan epidemic is primarily composed of …

Bayesian phylogenetic analysis of the influenza-A virus genomes isolated in Tunisia, and determination of potential recombination events

R Soli, B Kaabi, M Barhoumi, C Maktouf… - Molecular phylogenetics …, 2019 - Elsevier
The influenza-A virus (IAV) causes seasonal epidemics and presents a pandemic risk with
the possibility of genetic re-assortment, allowing the emergence of new strains. The …

An in vitro model to mimic selection of replication-competent HIV-1 intersubtype recombination in dual or superinfected patients

BS Bagaya, M Tian, GC Nickel, JF Vega, Y Li… - Journal of molecular …, 2017 - Elsevier
The low frequency of HIV-1 recombinants within entire viral populations in both individual
patients and culture-based infection models impedes investigation of the underlying factors …

Patterns of genomic site inheritance in HIV-1M inter-subtype recombinants delineate the most likely genomic sites of subtype-specific adaptation

M Tongo, T de Oliveira, DP Martin - Virus Evolution, 2018 - academic.oup.com
Recombination between different HIV-1 group M (HIV-1M) subtypes is a major contributor to
the ongoing genetic diversification of HIV-1M. However, it remains unclear whether the …

HIV and SIV evolution

BT Foley - Global virology II-HIV and neuroAIDS, 2017 - Springer
Abstract HIV-1 and HIV-2 both cause AIDS in humans, and both originated in nonhuman
primates in Africa before several cross-species transmission events introduced them into …

Elucidation of Early Evolution of HIV-1 Group M in the Congo Basin Using Computational Methods

M Tongo, DP Martin, JR Dorfman - Genes, 2021 - mdpi.com
The Congo Basin region is believed to be the site of the cross-species transmission event
that yielded HIV-1 group M (HIV-1M). It is thus likely that the virus has been present and …