Histidine as a key modulator of molecular self-assembly: Peptide-based supramolecular materials inspired by biological systems

Y Chen, K Tao, W Ji, VB Kumar, S Rencus-Lazar… - Materials Today, 2022 - Elsevier
Histidine, a versatile proteinogenic amino acid, plays a broad range of roles in all living
organisms and behaves as a key mediator of the interactions of biomolecules with inorganic …

Membrane internalization mechanisms and design strategies of arginine-rich cell-penetrating peptides

M Hao, L Zhang, P Chen - International Journal of Molecular Sciences, 2022 - mdpi.com
Cell-penetrating peptides (CPPs) have been discovered to deliver chemical drugs, nucleic
acids, and macromolecules to permeate cell membranes, creating a novel route for …

[HTML][HTML] Dual-sensitive antibacterial peptide nanoparticles prevent dental caries

P Zhang, S Wu, J Li, X Bu, X Dong, N Chen, F Li… - Theranostics, 2022 - ncbi.nlm.nih.gov
Background: Dental caries is the most prevalent bacterial biofilm-induced disease. Current
clinical prevention and treatment agents often suffer from adverse effects on oral microbiota …

Protein and Peptide‐Based Nanotechnology for Enhancing Stability, Bioactivity, and Delivery of Anthocyanins

L Zhang, L Yao, F Zhao, A Yu, Y Zhou… - Advanced …, 2023 - Wiley Online Library
Anthocyanin, a unique natural polyphenol, is abundant in plants and widely utilized in
biomedicine, cosmetics, and the food industry due to its excellent antioxidant, anticancer …

I-III-VI core/shell QDs: Synthesis, characterizations and applications

S Jain, S Bharti, GK Bhullar, SK Tripathi - Journal of Luminescence, 2020 - Elsevier
Colloidal semiconductor quantum dots (QDs) have proven to be ideal candidates for low
cost and high performance applications. From the past few decades, I-III-VI QDs have …

[HTML][HTML] Silk sericin-based biomaterials shine in food and pharmaceutical industries

C Yang, L Yao, L Zhang - Smart Materials in Medicine, 2023 - Elsevier
Silk sericin (SS) is a byproduct of the silk production process that consists of 18​ amino
acids and numerous polar groups. SS has a range of unique physical, chemical, and …

Nanoencapsulation of anthocyanin by an amphiphilic peptide for stability enhancement

L Yao, J Xu, L Zhang, L Liu, L Zhang - Food Hydrocolloids, 2021 - Elsevier
Generally, anthocyanin is extremely vulnerable when exposed to oxidants, alkaline, heat,
and metallic ions in the ambient environment. In this research, we use an amphiphilic …

Sericin “hairpin structure”-based multifunctional anthocyanin nanoencapsulation for remodeling ROS-dependent cutaneous wound healing

L Zhang, M Hao, L Yao, C Xing, Q Wen, Z Zhang… - Chemical Engineering …, 2023 - Elsevier
Anthocyanins, a class of polyphenols possessing potent antioxidant properties, are limited in
their applicability in biomedical industries owing to their low stability. This study harnessed …

Gene-editing by CRISPR–Cas9 in combination with anthracycline therapy via tumor microenvironment-switchable, EGFR-targeted, and nucleus-directed …

CS Wang, CH Chang, TY Tzeng, AMY Lin… - Nanoscale Horizons, 2021 - pubs.rsc.org
Head and neck cancer (HNC) has a high incidence and a poor prognosis. Epirubicin, a
topoisomerase inhibitor, is a potential anthracycline chemotherapeutic for HNC treatment …

pH-Activatable cell penetrating peptide dimers for potent delivery of anticancer drug to triple-negative breast cancer

SH Nam, J Jang, DH Cheon, SE Chong, JH Ahn… - Journal of Controlled …, 2021 - Elsevier
We developed a pH-activatable cell-penetrating peptide dimer LH 2 with histidine residues,
which can penetrate cells, specifically in weak acidic conditions, even at few tens of …