The chicken chorioallantoic membrane model in biology, medicine and bioengineering

P Nowak-Sliwinska, T Segura, ML Iruela-Arispe - Angiogenesis, 2014 - Springer
The chicken chorioallantoic membrane (CAM) is a simple, highly vascularized
extraembryonic membrane, which performs multiple functions during embryonic …

The CAM model—Q&A with experts

D Fischer, G Fluegen, P Garcia… - Cancers, 2022 - mdpi.com
Simple Summary The chorioallantoic membrane (CAM) model is an alternative in vivo test
system for the study of hallmarks of cancer such as angiogenesis, tumor growth, immune …

Chick Chorioallantoic Membrane (CAM) Assay as an In Vivo Model to Study the Effect of Newly Identified Molecules on Ovarian Cancer Invasion and Metastasis

NA Lokman, ASF Elder, C Ricciardelli… - International journal of …, 2012 - mdpi.com
The majority of ovarian cancer patients present with advanced disease and despite
aggressive treatment, prognosis remains poor. Significant improvement in ovarian cancer …

Microvascular experimentation in the chick chorioallantoic membrane as a model for screening angiogenic agents including from gene-modified cells

DC Kennedy, B Coen, AM Wheatley… - International journal of …, 2021 - mdpi.com
The chick chorioallantoic membrane (CAM) assay model of angiogenesis has been
highlighted as a relatively quick, low cost and effective model for the study of pro-angiogenic …

Optimization of the chicken chorioallantoic membrane assay as reliable in vivo model for the analysis of osteosarcoma

P Kunz, A Schenker, H Sähr, B Lehner, J Fellenberg - PLoS One, 2019 - journals.plos.org
Survival rates of osteosarcoma patients could not be significantly improved by conventional
chemotherapeutic treatment regimens since the introduction of high-dose chemotherapy 35 …

The in ovo chick chorioallantoic membrane (CAM) assay as an efficient xenograft model of hepatocellular carcinoma

M Li, RR Pathak, E Lopez-Rivera… - Journal of …, 2015 - pmc.ncbi.nlm.nih.gov
The chick chorioallantoic membrane (CAM) begins to develop by day 7 after fertilization and
matures by day 12. The CAM is naturally immunodeficient and highly vascularized, making it …

The in ovo CAM-assay as a xenograft model for sarcoma

GML Sys, L Lapeire, N Stevens… - Journal of …, 2013 - pmc.ncbi.nlm.nih.gov
Sarcoma is a very rare disease that is heterogeneous in nature, all hampering the
development of new therapies. Sarcoma patients are ideal candidates for personalized …

The effect of silver nanoparticles (AgNPs) on proliferation and apoptosis of in ovo cultured glioblastoma multiforme (GBM) cells

K Urbańska, B Pająk, A Orzechowski… - Nanoscale research …, 2015 - Springer
Recently, it has been shown that silver nanoparticles (AgNPs) provide a unique approach to
the treatment of tumors, especially those of neuroepithelial origin. Thus, the aim of this study …

Optimising the chick chorioallantoic membrane xenograft model of neuroblastoma for drug delivery

R Swadi, G Mather, BL Pizer, PD Losty, V See, D Moss - BMC cancer, 2018 - Springer
Background Neuroblastoma is a paediatric cancer that despite multimodal therapy still has a
poor outcome for many patients with high risk tumours. Retinoic acid (RA) promotes …

Grape seed proanthocyanidins inhibit colon cancer-induced angiogenesis through suppressing the expression of VEGF and Ang1

S Huang, N Yang, Y Liu, J Gao… - International …, 2012 - spandidos-publications.com
Tumor cells trigger angiogenesis through overexpression of various angiogenic factors
including vascular endothelial growth factor (VEGF) and angiopoietin 1 (Ang1). Therefore …