Lead phytochemicals for anticancer drug development

S Singh, B Sharma, SS Kanwar, A Kumar - Frontiers in plant science, 2016 - frontiersin.org
Cancer is a serious concern at present. A large number of patients die each year due to
cancer illnesses in spite of several interventions available. Development of an effective and …

Achillea spp.: A comprehensive review on its ethnobotany, phytochemistry, phytopharmacology and industrial applications

B Salehi, Z Selamoglu, M Sevindik… - Cellular and …, 2020 - mail.cellmolbiol.org
The genus Achillea genus houses more than 100 species, a number of them are popularly
used in traditional medicine for spasmodic gastrointestinal, gynecological and hepatobiliary …

An in vitro evaluation of the molecular mechanisms of action of medical plants from the Lamiaceae family as effective sources of active compounds against human …

P Sitarek, A Merecz-Sadowska, T Śliwiński, R Zajdel… - Cancers, 2020 - mdpi.com
Simple Summary Plants have been used in folk medicine for thousands of years. The
Lamiaceae family is one of the largest families of flowering plants and includes a wide …

Pharmacological properties and therapeutic potential of saffron (Crocus sativus L.) in osteosarcoma

B Ege, O Yumrutas, M Ege, M Pehlivan… - Journal of Pharmacy …, 2020 - academic.oup.com
Objectives In this comprehensive study, we aimed to investigate pharmacological properties
and therapeutic significance of saffron in osteosarcoma cancer cells. Methods Plant …

Invitro Antioxidant and Cytotoxic Activities of Extracts of Endemic Tanacetum erzincanense Together with Phenolic Content by LC‐ESI‐QTOF‐MS

İ Yapıcı, A Altay, B Öztürk Sarıkaya… - Chemistry & …, 2021 - Wiley Online Library
In this study, phenolic composition, and in vitro biological activities of ethyl acetate (EAE)
and methanol (ME) extracts obtained from the aerial parts of endemic Tanacetum …

Phytochemical Analysis, Antioxidant and Anticancer Potential of Sideritis niveotomentosa: Endemic Wild Species of Turkey

EN Şimşek Sezer, T Uysal - Molecules, 2021 - mdpi.com
Sideritis niveotomentosa Hub.-Mor. is a local endemic species belonging to the Lamiaceae
family. In this study, GC/MS analysis, total antioxidant capacity and anticancer effects of …

Siderol inhibits proliferation of glioblastoma cells and acts synergistically with temozolomide

M Giannakopoulou, K Dimitriadis, M Koromili, V Zoi… - Biomedicines, 2022 - mdpi.com
Glioblastoma (GBM) is the most aggressive primary central nervous system (CNS) tumor in
adults with dismal prognosis. Currently, the therapeutic interventions include gross total …

Chemical fingerprints, antioxidant, enzyme inhibitory, and cell assays of three extracts obtained from Sideritis ozturkii Aytaç & Aksoy: An endemic plant from Turkey

G Zengin, A Uğurlu, MC Baloglu, A Diuzheva… - … of pharmaceutical and …, 2019 - Elsevier
This study was geared towards assessing the possible antioxidant, enzyme inhibitory, and
cytotoxic activities of ethyl acetate, methanol, and water extracts of Sideritis ozturkii Aytaç & …

Cytotoxicity and Anti-cancer Activity of the Genus Achillea L.

K Papakosta, ME Grafakou, C Barda… - Current Medicinal …, 2020 - ingentaconnect.com
Background: The genus Achillea L. is rich in bioactive sesquiterpenes and flavonoids; most
of the studied species exhibit several biological activities and are used as emmenagogue …

Evaluation of cytotoxic, antifungal, and larvicidal activities of different bis‐sulfonamide Schiff base compounds

H Aydin, S Akocak, N Lolak, Ö Yumrutaş… - … of Biochemical and …, 2023 - Wiley Online Library
Schiff bases (imines or azomethines) are versatile ligands synthesized from the
condensation of amino compounds with active carbonyl groups and used for many …