Early-life body mass index and risks of breast, endometrial, and ovarian cancers: a dose–response meta-analysis of prospective studies

D Byun, SE Hong, S Ryu, Y Nam, H Jang, Y Cho… - British journal of …, 2022 - nature.com
Background The evidence for the associations between early-life adiposity and female
cancer risks is mixed. Little is known about the exact shape of the relationships and whether …

Automated percent mammographic density, mammographic texture variation, and risk of breast cancer: a nested case-control study

ET Warner, MS Rice, OA Zeleznik, EE Fowler… - NPJ Breast …, 2021 - nature.com
Percent mammographic density (PMD) is a strong breast cancer risk factor, however, other
mammographic features, such as V, the standard deviation (SD) of pixel intensity, may be …

A genome-wide association study of mammographic texture variation

Y Liu, H Chen, J Heine, S Lindstrom, C Turman… - Breast Cancer …, 2022 - Springer
Background Breast parenchymal texture features, including grayscale variation (V), capture
the patterns of texture variation on a mammogram and are associated with breast cancer …

Deep learning image analysis of benign breast disease to identify subsequent risk of breast cancer

AD Vellal, K Sirinukunwattan, KH Kensler… - JNCI Cancer …, 2021 - academic.oup.com
Background New biomarkers of risk may improve breast cancer (BC) risk prediction. We
developed a computational pathology method to segment benign breast disease (BBD) …

Joanne knight breast health cohort at siteman cancer center

GA Colditz, DL Bennett, J Tappenden, C Beers… - Cancer Causes & …, 2022 - Springer
Abstract Purpose The Joanne Knight Breast Health Cohort was established to link breast
cancer risk factors, mammographic breast density, benign breast biopsies and associated …

Associations of early-life and adult anthropometric measures with the expression of stem cell markers CD44, CD24, and ALDH1A1 in women with benign breast …

H Oh, L Yaghjyan, YJ Heng, B Rosner… - … Biomarkers & Prevention, 2024 - AACR
Background: According to the stem cell hypothesis, breast carcinogenesis may be related to
the breast stem cell pool size. However, little is known about associations of breast cancer …

Reproductive risk factors for breast cancer and association with novel breast density measurements among Hispanic, Black, and White women

ME Barnard, NC DuPré, JJ Heine, EE Fowler… - Breast Cancer Research …, 2024 - Springer
Purpose There are differences in the distributions of breast cancer incidence and risk factors
by race and ethnicity. Given the strong association between breast density and breast …

Reproductive factors related to childbearing and a novel automated mammographic measure, V

L Yaghjyan, Z Wang, ET Warner, B Rosner… - … Biomarkers & Prevention, 2024 - AACR
Background: We investigated the associations between several reproductive factors related
to childbearing and the variation (V) measure (a novel, objective, single summary measure …

Techniques to produce and evaluate realistic multivariate synthetic data

J Heine, EEE Fowler, A Berglund, MJ Schell… - Scientific Reports, 2023 - nature.com
Data modeling requires a sufficient sample size for reproducibility. A small sample size can
inhibit model evaluation. A synthetic data generation technique addressing this small …

Associations of oral contraceptives with mammographic breast density in premenopausal women

L Yaghjyan, C Smotherman, J Heine, GA Colditz… - … Biomarkers & Prevention, 2022 - AACR
Background: We investigated the associations of oral contraceptives (OC) with percent
breast density (PD), absolute dense area (DA), nondense area (NDA), and a novel image …