The prototypic head and neck squamous cell carcinoma (HNSCC) arises from the mucosal
lining of the upper aerodigestive tract, demonstrates squamous differentiation …

Abstract Treatment of locoregionally advanced head and neck squamous cell carcinoma
involves a multidisciplinary approach that combines surgery, radiotherapy, and systemic …

Background Patients with human papillomavirus (HPV)-positive oropharyngeal squamous
cell carcinoma have high survival when treated with radiotherapy plus cisplatin. Whether …

Background Patients with platinum-refractory recurrent or metastatic squamous cell
carcinoma of the head and neck have few treatment options and poor prognosis. Nivolumab …

BACKGROUND AND PURPOSE: To compare clinical outcomes and toxicities of two-
dimensional conventional radiation therapy (2D-CRT) and intensity modulated radiation …

Background Previous results from our phase 3 randomised trial showed that adding
cetuximab to primary radiotherapy increased overall survival in patients with locoregionally …

PURPOSE: To compare the results of intensity-modulated radiotherapy (IMRT) with those of
two-dimensional conventional radiotherapy (2D-CRT) in the treatment of patients with …

Over the last two decades, it has been recognized that head and neck cancers, primarily in
the oropharynx, can be a distinct entity that is causally related to human papilloma virus …

Head and neck cancer is becoming more common, and survival rates are improving. Human
papillomavirus–associated oropharyngeal cancer, in particular, is increasing in incidence …

Purpose To report results of a randomized phase II trial (Radiation Therapy Oncology Group
RTOG-0234) examining concurrent chemoradiotherapy and cetuximab in the postoperative …