Challenges and opportunities in developing targeted therapies for triple negative breast cancer
AG Chapdelaine, G Sun - Biomolecules, 2023 - mdpi.com
Triple negative breast cancer (TNBC) is a heterogeneous group of breast cancers
characterized by their lack of estrogen receptors, progesterone receptors, and the HER2 …
characterized by their lack of estrogen receptors, progesterone receptors, and the HER2 …
Shikonin blocks CAF-induced TNBC metastasis by suppressing mitochondrial biogenesis through GSK-3β/NEDD4-1 mediated phosphorylation-dependent …
S Fan, X Yan, X Hu, X Liu, S Zhao, Y Zhang… - Journal of Experimental …, 2024 - Springer
Background Triple-negative breast cancer (TNBC) is characterized by its high metastatic
potential, which results in poor patient survival. Cancer-associated fibroblasts (CAFs) are …
potential, which results in poor patient survival. Cancer-associated fibroblasts (CAFs) are …
[HTML][HTML] The Molecular Mechanisms behind Advanced Breast Cancer Metabolism: Warburg Effect, OXPHOS, and Calcium
E Mitaishvili, H Feinsod, Z David, J Shpigel… - Frontiers in …, 2024 - ncbi.nlm.nih.gov
Altered metabolism represents a fundamental difference between cancer cells and normal
cells. Cancer cells have a unique ability to reprogram their metabolism by deviating their …
cells. Cancer cells have a unique ability to reprogram their metabolism by deviating their …
Proteomic dynamics of breast cancer cell lines identifies potential therapeutic protein targets
Abstract Treatment and relevant targets for breast cancer (BC) remain limited, especially for
triple-negative BC (TNBC). We identified 6091 proteins of 76 human BC cell lines using data …
triple-negative BC (TNBC). We identified 6091 proteins of 76 human BC cell lines using data …
Mechanism of the Warburg effect and its role in breast cancer immunotherapy
ES Saheed, RF Aromolaran, AD Atoyebi, FC Adeleke… - Discover …, 2024 - Springer
Breast cancer remains a significant global health concern affecting millions of women
annually. An essential aspect of this disease is the Warburg effect, which is a metabolic …
annually. An essential aspect of this disease is the Warburg effect, which is a metabolic …
Proteomic Dynamics of Breast Cancers Identifies Potential Therapeutic Protein Targets
Abstract Treatment and relevant targets for breast cancer (BC) remain limited, especially for
triple-negative BC (TNBC). We quantified the proteomes of 76 human BC cell lines using …
triple-negative BC (TNBC). We quantified the proteomes of 76 human BC cell lines using …