[HTML][HTML] Automated subtyping of HIV-1 genetic sequences for clinical and surveillance purposes: performance evaluation of the new REGA version 3 and seven other …
Background To investigate differences in pathogenesis, diagnosis and resistance pathways
between HIV-1 subtypes, an accurate subtyping tool for large datasets is needed. We aimed …
between HIV-1 subtypes, an accurate subtyping tool for large datasets is needed. We aimed …
Characterization of HIV-associated neurocognitive disorders among individuals starting antiretroviral therapy in South Africa
Abstract HIV-Associated Neurocognitive Disorders (HAND) exert an impact on everyday
functions, including adherence. The prevalence of and risk factors for HAND in patients …
functions, including adherence. The prevalence of and risk factors for HAND in patients …
Analyses of HIV-1 integrase sequences prior to South African national HIV-treatment program and availability of integrase inhibitors in Cape Town, South Africa
HIV-Integrase (IN) has proven to be a viable target for highly specific HIV-1 therapy. We
aimed to characterize the HIV-1 IN gene in a South African context and identify resistance …
aimed to characterize the HIV-1 IN gene in a South African context and identify resistance …
Structural implications of genotypic variations in HIV-1 integrase from diverse subtypes
Human immunodeficiency virus type 1 (HIV-1) integrase (IN) integrates viral DNA into the
host genome using its 3′-end processing and strand-transfer activities. Due to the …
host genome using its 3′-end processing and strand-transfer activities. Due to the …
Neuroimaging markers of human immunodeficiency virus infection in South Africa
Previous studies have reported cognitive deficits among HIV-positive individuals infected
with clade C virus. However, no study has examined whether individuals predominately …
with clade C virus. However, no study has examined whether individuals predominately …
Association between apolipoprotein E4 genotype and human immunodeficiency virus-associated dementia in younger adults starting antiretroviral therapy in South …
It is not known whether the apolipoprotein E (ApoE) ε4 allelic variant is associated with
human immunodeficiency virus (HIV)-associated dementia (HAD) in a South African …
human immunodeficiency virus (HIV)-associated dementia (HAD) in a South African …
HIV-1 subtypes B and C unique recombinant forms (URFs) and transmitted drug resistance identified in the Western Cape Province, South Africa
South Africa has the largest worldwide HIV/AIDS population with 5.6 million people infected
and at least 2 million people on antiretroviral therapy. The majority of these infections are …
and at least 2 million people on antiretroviral therapy. The majority of these infections are …
Epidemiology of HIV-1 subtypes among men who have sex with men in Cape Town, South Africa
K Middelkoop, C Rademeyer, BB Brown… - JAIDS Journal of …, 2014 - journals.lww.com
Objective: Early studies in Cape Town identified independent HIV-1 epidemics, with distinct
viral subtypes, among men who have sex with men (MSM) and the heterosexual population …
viral subtypes, among men who have sex with men (MSM) and the heterosexual population …
Increases in CSF dopamine in HIV patients are due to the dopamine transporter 10/10-repeat allele which is more frequent in HIV-infected individuals
A Horn, C Scheller, S du Plessis, G Arendt… - Journal of Neural …, 2013 - Springer
Dysfunction of dopaminergic neurotransmission has been implicated in HIV infection. We
showed previously increased dopamine (DA) levels in CSF of therapy-naïve HIV patients …
showed previously increased dopamine (DA) levels in CSF of therapy-naïve HIV patients …
HIV-1 diversity in an antiretroviral treatment naïve cohort from Bushbuckridge, Mpumalanga Province, South Africa
PW Msimanga, E Vardas, S Engelbrecht - Virology journal, 2015 - Springer
Abstract Background South Africa has a generalized and explosive HIV/AIDS epidemic with
the largest number of people infected with HIV-1 in the world. Molecular investigations of …
the largest number of people infected with HIV-1 in the world. Molecular investigations of …