The promise of precision medicine in rheumatology

JM Guthridge, CA Wagner, JA James - Nature medicine, 2022 - nature.com
Systemic autoimmune rheumatic diseases (SARDs) exhibit extensive heterogeneity in
clinical presentation, disease course, and treatment response. Therefore, precision …

Exploring the intersection of artificial intelligence and clinical healthcare: a multidisciplinary review

CS Stafie, IG Sufaru, CM Ghiciuc, II Stafie, EC Sufaru… - Diagnostics, 2023 - mdpi.com
Artificial intelligence (AI) plays a more and more important role in our everyday life due to the
advantages that it brings when used, such as 24/7 availability, a very low percentage of …

Exploring the shared molecular mechanisms between systemic lupus erythematosus and primary Sjögren's syndrome based on integrated bioinformatics and single …

Y Cui, H Zhang, Z Wang, B Gong, H Al-Ward… - Frontiers in …, 2023 - frontiersin.org
Background Systemic lupus erythematosus (SLE) and primary Sjögren's syndrome (pSS)
are common systemic autoimmune diseases that share a wide range of clinical …

[HTML][HTML] Artificial intelligence and laboratory data in rheumatic diseases

P Galozzi, D Basso, M Plebani, A Padoan - Clinica Chimica Acta, 2023 - Elsevier
Artificial intelligence (AI)-based medical technologies are rapidly evolving into actionable
solutions for clinical practice. Machine learning (ML) algorithms can process increasing …

CD8+ T Cell Phenotype and Function in Childhood and Adult-Onset Connective Tissue Disease

A Radziszewska, Z Moulder, EC Jury… - International Journal of …, 2022 - mdpi.com
CD8+ T cells are cytotoxic lymphocytes that destroy pathogen infected and malignant cells
through release of cytolytic molecules and proinflammatory cytokines. Although the role of …

Current state and completeness of reporting clinical prediction models using machine learning in systemic lupus erythematosus: A systematic review

P Munguía-Realpozo, I Etchegaray-Morales… - Autoimmunity …, 2023 - Elsevier
Objective We carried out a systematic review (SR) of adherence in diagnostic and
prognostic applications of ML in SLE using the Transparent Reporting of a multivariable …

Recent advances in the use of machine learning and artificial intelligence to improve diagnosis, predict flares, and enrich clinical trials in lupus

KM Kingsmore, PE Lipsky - Current Opinion in Rheumatology, 2022 - journals.lww.com
Recent advances in the use of machine learning and artificia... : Current Opinion in
Rheumatology Recent advances in the use of machine learning and artificial intelligence to …

Memory CD4+ T cell profile is associated with unfavorable prognosis in IgG4-related disease: risk stratification by machine-learning

Y Nie, Z Liu, W Cao, Y Peng, H Lu, R Sun, J Li… - Clinical …, 2023 - Elsevier
Abstract IgG4-related disease (IgG4-RD) is a chronic immune-mediated disease with
heterogeneity. In this study, we used machine-learning approaches to characterize the …

Circulating CD8+ T Cell Subsets in Primary Sjögren's Syndrome

I Kudryavtsev, S Benevolenskaya, M Serebriakova… - Biomedicines, 2023 - mdpi.com
Currently, multiple studies have indicated that CD8+ T lymphocytes play a role in causing
damage to the exocrine glands through acinar injury in primary Sjögren's syndrome (pSS) …

Multi-omic biomarkers for patient stratification in sjogren's syndrome—a review of the literature

L Martin-Gutierrez, R Wilson, M Castelino, EC Jury… - Biomedicines, 2022 - mdpi.com
Sjögren's syndrome (SS) is a heterogeneous autoimmune rheumatic disease (ARD)
characterised by dryness due to the chronic lymphocytic infiltration of the exocrine glands …