Coumarin–benzimidazole hybrids: A review of developments in medicinal chemistry
Coumarin and benzimidazole are privileged structures in medicinal chemistry and are
widely used in drug discovery and development due to their vast biological properties. The …
widely used in drug discovery and development due to their vast biological properties. The …
Synthetic and natural coumarins as potent anticonvulsant agents: A review with structure–activity relationship
RS Keri, S Budagumpi… - Journal of Clinical …, 2022 - Wiley Online Library
What is known and objective The main objective of this review is to highlight the most
relevant studies since 1990 (to date) in the area of medicinal chemistry aspects to provide a …
relevant studies since 1990 (to date) in the area of medicinal chemistry aspects to provide a …
Imidazolinium chloride salts bearing wingtip groups: Synthesis, molecular docking and metabolic enzymes inhibition
A series of symmetrical imidazolinium chloride salts bearing secondary N-alkyl substituents
were synthesized in good yield by the reaction of N, N′-dialkylethane-1, 2-diamines and …
were synthesized in good yield by the reaction of N, N′-dialkylethane-1, 2-diamines and …
Drug interaction considerations in the therapeutic use of carbonic anhydrase inhibitors
CT Supuran - Expert opinion on drug metabolism & toxicology, 2016 - Taylor & Francis
ABSTRACT Introduction: Carbonic anhydrase inhibitors (CAIs) of the sulfonamide and
sulfamate type are clinically used drugs as diuretics, antiglaucoma, antiepileptic, antiobesity …
sulfamate type are clinically used drugs as diuretics, antiglaucoma, antiepileptic, antiobesity …
Novel NHC precursors: Synthesis, characterization, and carbonic anhydrase and acetylcholinesterase inhibitory properties
Three series of imidazolidinium ligands (NHC precursors) substituted with 4‐vinylbenzyl, 2‐
methyl‐1, 4‐benzodioxane, and N‐propylphthalimide were synthesized. N‐Heterocyclic …
methyl‐1, 4‐benzodioxane, and N‐propylphthalimide were synthesized. N‐Heterocyclic …
Novel N‐propylphthalimide‐ and 4‐vinylbenzyl‐substituted benzimidazole salts: Synthesis, characterization, and determination of their metal chelating effects and …
The novel N‐propylphthalimide‐substituted and 4‐vinylbenzyl‐substituted N‐heterocyclic
carbene (NHC) precursors were synthesized by N‐substituted benzimidazolium with aryl …
carbene (NHC) precursors were synthesized by N‐substituted benzimidazolium with aryl …
Molecular docking and anticonvulsant activity of newly synthesized quinazoline derivatives
HA Abuelizz, R El Dib, M Marzouk, EH Anouar… - Molecules, 2017 - mdpi.com
A new series of quinazoline-4 (3 H)-ones are evaluated for anticonvulsant activity. After
intraperitoneal (ip) injection to albino mice at a dose of 100 mg/kg body weight, synthesized …
intraperitoneal (ip) injection to albino mice at a dose of 100 mg/kg body weight, synthesized …
meta‐Cyanobenzyl substituted benzimidazolium salts: Synthesis, characterization, crystal structure and carbonic anhydrase, α‐glycosidase, butyrylcholinesterase …
F Türker, D Barut Celepci, A Aktaş… - Archiv der …, 2018 - Wiley Online Library
Abstract meta‐Cyanobenzyl‐substituted N‐heterocyclic carbene (NHC) precursors were
synthesized by the reaction of a series of N‐(alkyl) benzimidazolium with 3‐bromomethyl …
synthesized by the reaction of a series of N‐(alkyl) benzimidazolium with 3‐bromomethyl …
Evaluation of the status quo of polyphenols analysis: Part I—phytochemistry, bioactivity, interactions, and industrial uses
AS Silva, P Reboredo‐Rodríguez… - … Reviews in Food …, 2020 - Wiley Online Library
Phytochemicals, especially polyphenols, are gaining more attention from both the scientific
community and food, pharmaceutical, and cosmetics industries due to their implications in …
community and food, pharmaceutical, and cosmetics industries due to their implications in …
Novel amine-functionalized benzimidazolium salts: Synthesis, characterization, bioactivity, and molecular docking studies
A series of amine-tethered benzimidazolium salts were synthesized by the reactions
between 1-(1-methyl-2-dimethylaminoethyl) benzimidazole and various alkyl halides. The …
between 1-(1-methyl-2-dimethylaminoethyl) benzimidazole and various alkyl halides. The …