The production of plastic products, which requires phthalate plasticizers, has resulted in the
problems for human health, especially that of reproductive health. Phthalate exposure can …

For decades, studies of endocrine-disrupting chemicals (EDCs) have challenged traditional
concepts in toxicology, in particular the dogma of “the dose makes the poison,” because …

The purposes of this review are to (1) evaluate human and experimental evidence for
adverse effects on reproduction and development in humans, produced by exposure to …

Background Many phthalates and phenols are hormonally active and are suspected to alter
the course of development. Objective We investigated prenatal exposures to phthalate and …

Phthalate diesters are a diverse group of chemicals used to make plastics flexible and are
found in personal care products, medical equipment, and medication capsules. Ubiquitous …

Puberty presents remarkable individual differences in timing reaching over 5 years in
humans. We put emphasis on the two edges of the age distribution of pubertal signs in …

Background: Animal studies suggest that phthalates and bisphenol A (BPA), endocrine-
disrupting chemicals found in many consumer products, may impact the timing of puberty …

Experimental animal studies have demonstrated that exposure to some phthalates may be
associated with altered endocrine function and adverse effects on male reproductive …

Background There is limited epidemiological evidence on the association of prenatal
exposure to phthalates and synthetic phenols with altered pubertal timing. Objective To …

Abstract Di-(2-ethylhexyl) phthalate (DEHP) is used extensively in many personal care and
consumer products, resulting in widespread nonoccupational human exposure through …