Hepatitis E virus: advances and challenges
At least 20 million hepatitis E virus (HEV) infections occur annually, with> 3 million
symptomatic cases and∼ 60,000 fatalities. Hepatitis E is generally self-limiting, with a case …
symptomatic cases and∼ 60,000 fatalities. Hepatitis E is generally self-limiting, with a case …
Conventional and unconventional mechanisms for capping viral mRNA
In the eukaryotic cell, capping of mRNA 5′ ends is an essential structural modification that
allows efficient mRNA translation, directs pre-mRNA splicing and mRNA export from the …
allows efficient mRNA translation, directs pre-mRNA splicing and mRNA export from the …
Update on hepatitis E virology: Implications for clinical practice
Hepatitis E virus (HEV) is a positive-strand RNA virus transmitted by the fecal-oral route. The
7.2 kb genome encodes three open reading frames (ORF) which are translated into (i) the …
7.2 kb genome encodes three open reading frames (ORF) which are translated into (i) the …
Hepatitis E virus
SU Emerson, RH Purcell - Reviews in medical virology, 2003 - Wiley Online Library
Hepatitis E virus (HEV) is a positive‐stranded RNA virus with a 7.2 kb genome that is
capped and polyadenylated. The virus is currently unclassified: the organisation of the …
capped and polyadenylated. The virus is currently unclassified: the organisation of the …
Molecular virology of hepatitis E virus
This review details the molecular virology of the hepatitis E virus (HEV). While replicons and
in vitro infection systems have recently become available, a lot of information on HEV has …
in vitro infection systems have recently become available, a lot of information on HEV has …
Genetic variability and evolution of hepatitis E virus
H Okamoto - Virus research, 2007 - Elsevier
Hepatitis E virus (HEV) is the sole member of the genus Hepevirus in the family Hepeviridae.
HEV is transmitted primarily by the fecal–oral route, and water-borne epidemics are …
HEV is transmitted primarily by the fecal–oral route, and water-borne epidemics are …
Viral RNA replication in association with cellular membranes
A Salonen, T Ahola, L Kääriäinen - Membrane trafficking in viral replication, 2005 - Springer
All plus-strand RNA viruses replicate in association with cytoplasmic membranes of infected
cells. The RNA replication complex of many virus families is associated with the …
cells. The RNA replication complex of many virus families is associated with the …
Hepatitis E virus genome structure and replication strategy
Hepatitis E virus (HEV) possesses many of the features of other positive-stranded RNA
viruses but also adds HEV-specific nuances, making its virus–host interactions unique. Slow …
viruses but also adds HEV-specific nuances, making its virus–host interactions unique. Slow …
A bicistronic subgenomic mRNA encodes both the ORF2 and ORF3 proteins of hepatitis E virus
J Graff, U Torian, H Nguyen, SU Emerson - Journal of virology, 2006 - Am Soc Microbiol
Hepatitis E virus replicons containing the neomycin resistance gene expressed from open
reading frames (ORFs) 2 and 3 were transfected into Huh-7 cells, and stable cell lines …
reading frames (ORFs) 2 and 3 were transfected into Huh-7 cells, and stable cell lines …
Structure of the hepatitis E virus-like particle suggests mechanisms for virus assembly and receptor binding
Hepatitis E virus (HEV), a small, non-enveloped RNA virus in the family Hepeviridae, is
associated with endemic and epidemic acute viral hepatitis in developing countries. Our 3.5 …
associated with endemic and epidemic acute viral hepatitis in developing countries. Our 3.5 …