The immune-inflammatory response is associated with increased nitro-oxidative stress. The
aim of this mechanistic review is to examine:(a) the role of redox-sensitive transcription …

Natural killer (NK) cells, which are innate lymphocytes endowed with potent cytotoxic
activity, have recently attracted attention as potential anticancer therapeutics. While NK cells …

Ferroptosis is a recently recognized cell death modality that is morphologically,
biochemically and genetically distinct from other forms of cell death and that has emerged to …

Regulated cell death (RCD) has a significant impact on development, tissue homeostasis,
and the occurrence of various diseases. Among different forms of RCD, ferroptosis is …

Reactive oxygen species (ROS) play a pivotal role in biological processes and continuous
ROS production in normal cells is controlled by the appropriate regulation between the silver …

Innate and adaptive immune cell activation and infiltration is the key characteristic of tissue
inflammation. The innate immune system is the front line of host defense in which innate …

Reactive oxygen species (ROS) are a group of short-lived highly reactive molecules formed
intracellularly from molecular oxygen. ROS can alter biochemical, transcriptional, and …

Cancer is a disease which frequently has a poor prognosis. Although multiple therapeutic
strategies have been developed for various cancers, including chemotherapy, radiotherapy …

Cancer-associated fibroblasts (CAF) represent a functionally heterogeneous population of
activated fibroblasts that constitutes a major component of tumor stroma. Although CAFs …

The role of neutrophils in solid tumor metastasis remains largely controversial. In preclinical
models of solid tumors, both pro-metastatic and anti-metastatic effects of neutrophils have …