Fungal infections are on the rise, driven by a growing population at risk and climate change.
Currently available antifungals include only five classes, and their utility and efficacy in …

Amphotericin B has long been crucial for treating many serious infectious diseases, such as
invasive fungal infections and visceral leishmaniasis, particularly for patients who are …

Background Invasive fungal infections (IFI) present a major medical challenge, with an
estimated 6.5 million cases annually, resulting in 3.8 million deaths. Pathogens such as …

Cryptococcus neoformans causes cryptococcosis, one of the most prevalent fungal
diseases, generally characterized by meningitis. There is a limited and not very effective …

Background Limited data exist on the antifungal activity of daily liposomal amphotericin B
with flucytosine induction regimens for cryptococcal meningitis, which are recommended in …

Abstract Background In the Balkans, rising concerns about invasive fungal infections over
the past decade stem from various factors. Primarily, there has been a notable uptick in …

Introduction Advances in diagnostic technologies, particularly Point-of-Care Diagnostics
(POCDs), have revolutionized clinical practice by providing rapid, user-friendly, and …

Limited antifungal treatment options and drug resistance require innovative approaches to
effectively combat fungal infections. Combination therapy is a promising strategy that …

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Background Cryptococcosis is an invasive infection that commonly affects
immunosuppressed individuals, especially patients with HIV infection. Cryptococcal infection …