Quinoline anticancer agents active on DNA and DNA-interacting proteins: From classical to emerging therapeutic targets

A Lauria, G La Monica, A Bono, A Martorana - European Journal of …, 2021 - Elsevier
Quinoline is one of the most important and versatile nitrogen heterocycles embodied in
several biologically active molecules. Within the numerous quinolines developed as …

[HTML][HTML] A review on quinoline hydrazone derivatives as a new class of potent antitubercular and anticancer agents

MC Mandewale, UC Patil, SV Shedge… - Beni-Suef University …, 2017 - Elsevier
Tuberculosis (TB) and Cancer remains a global public health problem in recent years. There
is an urgent need for the screening of new bioactive molecules with new targets and with a …

A novel water soluble ligand bridged cobalt (II) coordination polymer of 2-oxo-1, 2-dihydroquinoline-3-carbaldehyde (isonicotinic) hydrazone: evaluation of the DNA …

DS Raja, NSP Bhuvanesh, K Natarajan - Dalton Transactions, 2012 - pubs.rsc.org
A novel water soluble ligand-bridged cobalt (II) coordination polymer has been synthesized
by reacting the new ligand, 2-oxo-1, 2-dihydroquinoline-3-carbaldehyde (isonicotinic) …

Synthesis, characterization, and biological activities of novel vanadium (IV) and cobalt (II) complexes

T Damena, D Zeleke, T Desalegn, TB Demissie… - ACS …, 2022 - ACS Publications
Herein, we report novel Co (II) and V (IV) complexes synthesized from an (E)-2-(((2-((2-
hydroxyethyl) amino) quinolin-3-yl) methylene) amino) ethan-1-ol ligand (L), cobalt (II) …

Potentially cytotoxic new copper (II) hydrazone complexes: synthesis, crystal structure and biological properties

M Alagesan, NSP Bhuvanesh, N Dharmaraj - Dalton Transactions, 2013 - pubs.rsc.org
A new set of penta-coordinated copper (II) hydrazone complexes containing solvated
methanol were synthesized by reacting the hydrazone ligands, 2-acetylpyridine benzoyl …

[HTML][HTML] A novel Schiff base derived from the gabapentin drug and copper (II) complex: Synthesis, characterization, interaction with DNA/protein and cytotoxic activity

Z Shokohi-Pour, H Chiniforoshan… - … of Photochemistry and …, 2016 - Elsevier
A novel Schiff base [C 20 H 23 NO 3], has been prepared and characterized using FT-IR, UV–
vis, 1 H NMR spectroscopy, elemental analysis and X-ray crystallography. A copper (II) …

Chemodynamic therapy agents Cu (II) complexes of quinoline derivatives induced ER stress and mitochondria-mediated apoptosis in SK-OV-3 cells

WY Shen, CP Jia, AN Mo, H Liang, ZF Chen - European Journal of …, 2021 - Elsevier
Three Cu (II) complexes of quinoline derivatives as cancer chemodynamic therapy agents
were synthesized and characterized. These complexes were heavily taken up by cells and …

Synthesis, structure and molecular docking studies of dicopper (II) complexes bridged by N-phenolato-N′-[2-(dimethylamino) ethyl] oxamide: the influence of terminal …

K Zheng, F Liu, XM Xu, YT Li, ZY Wu… - New Journal of …, 2014 - pubs.rsc.org
Two dicopper (II) complexes bridged by N-phenolato-N′-[2-(dimethylamino) ethyl] oxamide
(H3pdmaeox) and end-capped with 2, 2′-diamino-4, 4′-bithiazole (dabt) and 2, 2 …

Synthesis and computational studies of novel cobalt (II) and oxovanadium (IV) complexes of quinoline carbaldehyde derivative ligand for antibacterial and antioxidant …

T Damena, MB Alem, D Zeleke, TB Demissie… - Journal of Molecular …, 2023 - Elsevier
Novel metal complexes [Co (HL) 2 (H 2 O) 2)](1) and [VO (HL) 2](2) were synthesized using
2-((2-hydroxyethyl) amino) quinoline-3-carbaldehyde, ligand in 1: 2 metal–ligand ratio in …

Copper (II) complex enhanced chemodynamic therapy through GSH depletion and autophagy flow blockade

WY Shen, CP Jia, LY Liao, LL Chen, CC Yuan… - Dalton …, 2023 - pubs.rsc.org
Three copper (II) complexes C1–C3 were synthesized and fully characterized as
chemodynamic therapy (CDT) anticancer agents. C1–C3 showed greater cytotoxicity than …