Fast and effective detection of the causative agent of malaria in humans, protozoan
Plasmodium parasites, is of crucial importance for increasing the effectiveness of treatment …

The malaria parasite has co‐evolved with its human host as each organism struggles for
resources and survival. The scars of this war are carried in the human genome in the form of …

Plasmodium falciparum malaria causes morbidity and mortality in African children with sickle
cell anemia (SCA), but comparisons of host responses to P falciparum between children with …

Plasmodium falciparum infections can cause severe malaria, but not every infected person
develops life-threatening complications. In particular, carriers of the structural …

As parasites, Plasmodium species depend upon their host for survival. During the blood
stage of their life-cycle parasites invade and reside within erythrocytes, commandeering host …

During intraerythrocytic development, Plasmodium falciparum increases the ion permeability
of the erythrocyte plasma membrane to an extent that jeopardizes the osmotic stability of the …

The life cycle of malaria parasites in both their mammalian host and mosquito vector
consists of multiple developmental stages that ensure proper replication and progeny …

Plasmodium falciparum blood stages export a large number of proteins into their host red
blood cell, leading to changes to the infected cell that are pivotal for parasite survival and …

Hemoglobin variants C and S protect against severe malaria but their influence on
parameters not directly linked to disease severity such as gametocyte carriage and infection …

Epidemiological indicators describing population-level malaria transmission dynamics are
widely used to guide policy recommendations. However, the determinants of malaria …