6‐Gingerol, a Major Ingredient of Ginger Attenuates Diethylnitrosamine‐Induced Liver Injury in Rats through the Modulation of Oxidative Stress and Anti‐Inflammatory …

MA Alsahli, SA Almatroodi, A Almatroudi… - Mediators of …, 2021 - Wiley Online Library
Diethylnitrosamine (DEN) is a well‐known hepatocarcinogen, and its oral administration
causes severe liver damage including cancer. DEN induces the pathogenesis of the liver …

[HTML][HTML] Simvastatin induces cell cycle arrest and inhibits proliferation of bladder cancer cells via PPARγ signalling pathway

G Wang, R Cao, Y Wang, G Qian, HC Dan, W Jiang… - Scientific reports, 2016 - nature.com
Simvastatin is currently one of the most common drugs for old patients with hyperlipidemia,
hypercholesterolemia and atherosclerotic diseases by reducing cholesterol level and anti …

[HTML][HTML] EMT markers in locally-advanced prostate cancer: predicting recurrence?

KA Cheaito, HF Bahmad, O Hadadeh, E Saleh… - Frontiers in …, 2019 - frontiersin.org
Background: Prostate cancer (PCa) is the second most frequent cause of cancer-related
death in men worldwide. It is a heterogeneous disease at molecular and clinical levels …

PPARγ inhibition regulates the cell cycle, proliferation and motility of bladder cancer cells

S Cheng, K Qian, Y Wang, G Wang… - Journal of cellular …, 2019 - Wiley Online Library
Peroxisome proliferator‐activated receptor gamma (PPARγ) is a member of the nuclear
receptor family of ligand‐activated transcription factors and plays an important role in …

[HTML][HTML] Protective effect of quercetin, a Flavonol against benzo (a) pyrene-induced lung injury via inflammation, oxidative stress, angiogenesis and Cyclooxygenase-2 …

MA Alzohairy, AA Khan, MA Ansari, AY Babiker… - Applied Sciences, 2021 - mdpi.com
Quercetin (Qu) is an important polyphenolic flavonoid which exhibits tremendous
antioxidant, anti-inflammatory and other health promoting effects. The aim of the current …

The Immunohistochemical Staining of Vimentin and E-Cadherin in Bladder Cancer Patients Infected with Hepatitis C Virus.

MK Ismael, YB Qaddoori, MN Shaban… - Journal of Pure & …, 2023 - search.ebscohost.com
The invasion and spread of cancer cells are two of the most notable characteristics of
malignant tumors. Recent studies suggest that the epithelial-mesenchymal transition (EMT) …

[HTML][HTML] Prognostic significance of vascular endothelial growth factor (VEGF) and Her-2 protein in the genesis of cervical carcinoma

AH Rahmani, AY Babiker, MA Alsahli… - … journal of medical …, 2018 - ncbi.nlm.nih.gov
BACKGROUND: Angiogenesis plays a pivotal role in the progression of tumours through the
formation of new blood vessels. Vascular endothelial growth factor (VEGF) is a chief factor …

High P2X6 receptor expression in human bladder cancer predicts good survival prognosis

F Dietrich, AR Cappellari, EC Filippi-Chiela… - Molecular and Cellular …, 2022 - Springer
As alterations in purinergic signaling have been observed in bladder diseases, we aimed to
assess the potential prognostic role of purinergic receptors in bladder cancer in a …

[HTML][HTML] Quantitative proteomics of urinary bladder cancer cell lines identify UAP1 as a potential therapeutic target

VN Puttamallesh, B Deb, K Gondkar, A Jain, B Nair… - Genes, 2020 - mdpi.com
Bladder carcinoma (BC) incidence and mortality rates are increasing worldwide. The
development of novel therapeutic strategies is required to improve clinical management of …

[HTML][HTML] Epigallocatechin-3-gallate (EGCG), an active constituent of green tea: implications in the prevention of liver injury induced by diethylnitrosamine (DEN) in rats

S A. Almatroodi, M A. Alsahli, HM Alharbi, AA Khan… - Applied Sciences, 2019 - mdpi.com
Featured Application EGCG, an active constituent of green tea acts as a hepatoprotectant by
reducing the serum levels of liver functional enzymes, increasing total anti-oxidative …