Peripheral nerve injuries usually lead to severe loss of motor, sensory and autonomic
functions in the patients. Due to the complex requirements for adequate axonal …

The experimental model of choice for many peripheral nerve investigators is the rat. Walking
track analysis is a useful tool in the evaluation of functional peripheral nerve recovery in the …

The significant drawbacks and lack of success associated with current methods to treat
critically sized nerve defects have led to increased interest in neural tissue engineering …

Autografting is the gold standard in the repair of peripheral nerve injuries that are not
amenable to end‐to‐end coaptation. However, because autografts result in donor‐site …

Animal models of nerve compression, crush, and transection injuries of peripheral nerves
have been subject to extensive study in order to understand the mechanisms of injury and …

Written by more than 400 subject experts representing diverse academic and applied
domains, this multidisciplinary resource surveys the vanguard of biomaterials and …

This study attempted to enhance the efficacy of peripheral nerve regeneration using our
previously tested poly (l-lactic acid)(PLLA) conduits by incorporating them with allogeneic …

Nerve crush is a commonly used experimental model in the rat; however, a standard method
of inducing this injury has not been defined. This study examined six crush techniques that …

The present study provides in vivo trials of poly (l-lactic acid)(PLLA) as a porous
biodegradable nerve conduit using a 10mm sciatic nerve defect model in rats. The PLLA …

Background If a critical nerve is circumferentially involved with tumor, radical surgery
intended to cure the cancer must sacrifice the nerve. Loss of critical nerves may lead to …