Despite the plethora of empirical studies conducted to date, debate continues about whether
and to what extent results should be returned to participants of genomic research. We aimed …

Purpose As whole-exome sequencing (WES) and whole-genome sequencing (WGS) move
into routine clinical practice, it is timely to review data that might inform the debate regarding …

In clinical exome and genome sequencing, there is a potential for the recognition and
reporting of incidental or secondary findings unrelated to the indication for ordering the …

Purpose: We describe parental attitudes toward the return of targeted and incidental
genomic research results in the setting of high-risk pediatric cancer and inherited childhood …

With the development of next generation sequencing, beyond identifying the cause of
manifestations that justified prescription of the test, other information with potential interest …

The potential for genomic incidental findings is increasing with the use of genome‐based
testing. At the same time approaches to clinical decision making are shifting to shared …

Over the past decade, there has been an extensive debate about whether researchers have
an obligation to disclose genetic research findings, including primary and secondary …

The success of biobank-based genomic research is widely dependent on people's
willingness to donate their tissue. Thus, stakeholders' opinions should be considered in the …

Next-generation sequencing (NGS) technologies allow for the generation of whole exome or
whole genome sequencing data, which can be used to identify novel genetic alterations …

While the development of next-generation sequencing technology has had a paradigm-
changing impact on biomedical research, there is likely to be a gap between discovery of …