Psychiatric disorders affect 970 million people worldwide, representing a significant source
of disability. Although the underlying neurobiological traits for these disorders are not fully …

Human central nervous system myelin development extends well into the fourth decade of
life, and this protracted period underscores the potential for experience to modulate …

Background Genome-wide association studies have identified several common risk loci for
schizophrenia (SCZ). In parallel, neuroimaging studies have shown consistent findings of …

The notion that healthy brain function emerges from coordinated neural activity constrained
by the brain's network of anatomical connections—ie, the connectome—suggests that …

Bipolar disorder (BD) is a major psychiatric illness with a chronic recurrent course, ranked
among the worldwide leading disabling diseases. Its pathophysiology is still not completely …

Abnormalities of brain connectivity and signal transduction are consistently observed in
individuals with schizophrenias (SZ). Underlying these anomalies, convergent in vivo, post …

Alterations in the myelination of the cerebral cortex may underlie abnormal cortical function
in a variety of brain diseases. Here, we describe a technique for investigating changes in …

Cognitive impairment is a prominent feature of bipolar disorder (BD), however the neural
substrates underpinning it remain unclear. Several studies have explored white matter as a …

Introduction Brain white matter (WM) abnormalities are biomarkers that seem to be involved
in bipolar disorder (BD) aetiology and maintenance. Evidences suggest a possible …

Severe mental illnesses (SMI) such as schizophrenia and bipolar disorder affect 2-4% of the
world population. Current medications and diagnostic methods for mental illnesses are not …