Osteosarcoma is the most common primary malignant bone tumor, predominantly occurring
in children and adolescents. Despite treated with surgery and neoadjuvant chemotherapy …

Sarcomas are uncommon malignancies of mesenchymal origin that can arise throughout the
human lifespan, at any part of the body. Surgery remains the optimal treatment modality …

Renal cell carcinoma (RCC) is a malignant tumor of the kidneys. Approximately 70% of RCC
cases are clear cell renal cell carcinoma with von Hippel–Lindau (VHL) gene mutation and …

Osteosarcoma, one of the common malignant tumors in the skeletal system, originates in
mesenchymal tissue, and the most susceptible area of occurrence is the metaphysis with its …

Osteosarcoma (OS) is a malignant solid tumor prone to lung metastasis that occurs in
adolescents aged 15–19 years. Neoadjuvant chemotherapy and surgical treatment aimed at …

MicroRNAs (miRNAs) are well-known regulators of biological mechanisms with a small size
of 19–24 nucleotides and a single-stranded structure. miRNA dysregulation occurs in cancer …

Aims The morbidity and mortality rates of calcific aortic valve disease (CAVD) remain high
while treatment options are limited. Here, we evaluated the role and therapeutic value of …

The exploration of drugs derived from natural sources holds significant promise in
addressing current limitations in ovarian cancer (OC) treatments. While previous studies …

Hepatocellular carcinoma (HCC) is one of the deadliest malignant tumors that are harmful to
human health. Increasing evidence has underscored the critical role of the competitive …

Backgrounds Osteosarcomas are one of the most common primary malignant tumors of
bone. It primarily occurs in children and adolescents, with the second highest incidence …