ADAM (a disintegrin and metalloprotease) proteins are membrane-anchored
metalloproteases that process and shed the ectodomains of membrane-anchored growth …

The world's population is increasing at an alarming rate and is projected to reach nine billion
by 2050. Despite this, 15% of couples world-wide remain childless because of infertility. Few …

Understanding mammalian spermatozoan development and the events surrounding
fertilization has grown slowly, in part because of uncertainty about the number and identity of …

Mammalian fertilization comprises sperm migration through the female reproductive tract,
biochemical and morphological changes to sperm, and sperm-egg interaction in the oviduct …

Proteolytic enzymes belonging to the A Disintegin And Metalloproteinase (ADAM) family are
able to cleave transmembrane proteins close to the cell surface, in a process referred to as …

The oviduct or Fallopian tube is the anatomical region where every new life begins in
mammalian species. After a long journey, the spermatozoa meet the oocyte in the specific …

Fertilization is defined as the process of union of two gametes, eggs and sperm. When
mammalian eggs and sperm come into contact in the female oviduct, a series of steps is set …

Fertilization is the process by which eggs and spermatozoa interact, achieve mutual
recognition, and fuse to create a zygote, which then develops to form a new individual, thus …

Fertilization is the sum of the cellular mechanisms that pass the genome from one
generation to the next and initiate development of a new organism. A typical, ovulated …

Fertilization is the fusion of the male and female gamete. The process involves the fusion of
an oocyte with a sperm, creating a single diploid cell, the zygote, from which a new …