Nanoparticle probes for the detection of cancer biomarkers, cells, and tissues by fluorescence

AB Chinen, CM Guan, JR Ferrer, SN Barnaby… - Chemical …, 2015 - ACS Publications
Cancer is the second most common cause of death in the United States, trailing only heart
disease in incidence. Despite significant worldwide investment in research, cancer remains …

Nanomaterials for theranostics: recent advances and future challenges

EK Lim, T Kim, S Paik, S Haam, YM Huh… - Chemical reviews, 2015 - ACS Publications
In 2004, the US Food and Drug Administration (FDA) released an important report entitled
“Innovation/Stagnation: Challenge and Opportunity on the Critical Path to New Medical …

Engineered extracellular vesicles as intelligent nanosystems for next-generation nanomedicine

Z Fan, C Jiang, Y Wang, K Wang, J Marsh… - Nanoscale …, 2022 - pubs.rsc.org
Extracellular vesicles (EVs), as natural carriers of bioactive cargo, have a unique
micro/nanostructure, bioactive composition, and characteristic morphology, as well as …

Rationally designed molecular beacons for bioanalytical and biomedical applications

J Zheng, R Yang, M Shi, C Wu, X Fang, Y Li… - Chemical Society …, 2015 - pubs.rsc.org
Nucleic acids hold promise as biomolecules for future applications in biomedicine and
biotechnology. Their well-defined structures and compositions afford unique chemical …

Programmable and multifunctional DNA‐based materials for biomedical applications

Y Zhang, J Tu, D Wang, H Zhu, SK Maity… - Advanced …, 2018 - Wiley Online Library
DNA encodes the genetic information; recently, it has also become a key player in material
science. Given the specific Watson–Crick base‐pairing interactions between only four types …

[HTML][HTML] Smart drug delivery systems for precise cancer therapy

X Wang, C Li, Y Wang, H Chen, X Zhang, C Luo… - … Pharmaceutica Sinica B, 2022 - Elsevier
Nano-drug delivery strategies have been highlighted in cancer treatment, and much effort
has been made in the optimization of bioavailability, biocompatibility, pharmacokinetics …

A multicolor nanoprobe for detection and imaging of tumor‐related mRNAs in living cells

N Li, C Chang, W Pan, B Tang - … Chemie International Edition, 2012 - Wiley Online Library
Cancer is a leading cause of death worldwide and accounts for several millions of deaths
every year.[1] The survival of cancer patients is strongly associated with the stage of the …

Multiplexed detection and imaging of intracellular mRNAs using a four-color nanoprobe

W Pan, T Zhang, H Yang, W Diao, N Li… - Analytical …, 2013 - ACS Publications
Simultaneous detection and imaging of multiple intracellular biomarkers hold great promise
for early cancer detection. Here, we introduce a four-color nanoprobe that can …

Gold nanoparticle delivery of modified CpG stimulates macrophages and inhibits tumor growth for enhanced immunotherapy

AY Lin, JP Mattos Almeida, A Bear, N Liu, L Luo… - PloS one, 2013 - journals.plos.org
Gold nanoparticle accumulation in immune cells has commonly been viewed as a side effect
for cancer therapeutic delivery; however, this phenomenon can be utilized for developing …

Bioapplications of cell-SELEX-generated aptamers in cancer diagnostics, therapeutics, theranostics and biomarker discovery: a comprehensive review

X Pang, C Cui, S Wan, Y Jiang, L Zhang, L Xia, L Li… - Cancers, 2018 - mdpi.com
Currently, functional single-stranded oligonucleotide probes, termed aptamers, generated
by an iterative technology, Systematic Evolution of Ligands by Exponential Enrichment …