Severe covid-19 pneumonia has posed critical challenges for the research and medical
communities. Older age, male sex, and comorbidities increase the risk for severe disease …

Introduction Typical acute respiratory distress syndrome (ARDS) and severe coronavirus-19
(COVID-19) pneumonia share complex pathophysiology, a high mortality rate, and an unmet …

We described features of hospitalized Covid-19 patients and identified predictors of clinical
deterioration. We included patients consecutively admitted at Humanitas Research Hospital …

Background In acute respiratory distress syndrome (ARDS), non-ventilated perfused regions
coexist with non-perfused ventilated regions within lungs. The number of unmatched regions …

Acute respiratory distress syndrome (ARDS) is a severe form of respiratory failure burden by
high hospital mortality. No specific pharmacologic treatment is currently available and its …

Acute respiratory distress syndrome (ARDS) is a serious complication of severe systemic or
local pulmonary inflammation, such as caused by severe acute respiratory syndrome …

Abstract Coronavirus disease-2019 (COVID-19) may severely affect respiratory function and
evolve to life-threatening hypoxia. The clinical experience led to the implementation of …

Objectives: Hysteresis of the respiratory system pressure-volume curve is related to alveolar
surface forces, lung stress relaxation, and tidal reexpansion/collapse. Hysteresis has been …

Simple Summary The balanced matching of air and blood flow in the lungs is crucial for
maintaining oxygen levels and clearing carbon dioxide. In patients with severe respiratory …

Cumulative evidence has demonstrated that the ventilatory ratio closely correlates with
mortality in acute respiratory distress syndrome (ARDS), and a primary feature in …