OBJECTIVES: TIMPs control the activity of MMPs, one of the key molecules for tumor
invasion and metastasis. The aim of this study was to assess the usefulness of MMP-2 and …

Background The molecular mechanisms of the development and progression of bladder
cancer are poorly understood. The objective of this study was to analyze the expression of …

Recent evidence on molecular pathways helps us to understand the pathogenesis of
bladder cancer. However, the molecular mechanisms of recurrence of the disease and …

This study was conducted to analyze the expression of the ubiquitin-specific protease Usp28
and assess its clinical significance in human bladder cancer. mRNA and protein expression …

Objectives: The reliable detection of bladder cancer from urine specimen remains an
unsolved problem. Especially superficial bladder cancer can be missed with urine tests. We …

The accumulation of genetic alterations plays a role in the evolution of bladder cancer.
These changes can be detected in the urine by DNA analysis of the cells exfoliated from the …

Cancer is a major and increasing public health problem worldwide. Traditionally, the
diagnosis and staging of cancer, as well as the evaluation of response to therapy have been …

BACKGROUND A new, sensitive, noninvasive method for the detection of urothelial
carcinomas of the urinary bladder would open new possibilities in both the diagnosis and …

OBJECTIVES:: To develop bladder cancer-specific ligands using a combinatorial chemistry
approach. MATERIALS AND METHODS:: We performed a high-throughput one-bead one …

Objectives. Plasma hyaluronan is a potentially useful clinical test, especially in liver disease.
It rises after eating, but mechanisms by which this occurs are not known. The study aimed at …