The target of rapamycin (TOR), discovered 30 years ago, is a highly conserved
serine/threonine protein kinase that plays a central role in regulating cell growth and …

The mTOR pathway integrates a diverse set of environmental cues, such as growth factor
signals and nutritional status, to direct eukaryotic cell growth. Over the past two and a half …

Translational control of mRNAs during gene expression allows cells to promptly and
dynamically adapt to a variety of stimuli, including in neoplasia in response to aberrant …

The highly conserved protein kinase mechanistic target of rapamycin (mTOR; originally
known as mammalian target of rapamycin) is a central cell growth regulator connecting …

The aim of this review was to summarize current available information about the role of
phosphatidylinositol-3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR) signaling …

The mechanistic target of rapamycin (mTOR) coordinates eukaryotic cell growth and
metabolism with environmental inputs, including nutrients and growth factors. Extensive …

The mechanistic target of rapamycin complex 1 (mTORC1) signaling hub integrates multiple
environmental cues to modulate cell growth and metabolism. Over the past decade …

mTOR [mechanistic target of rapamycin] is a serine/threonine protein kinase that, as part of
mTORC1 (mTOR complex 1), acts as an important molecular connection between nutrient …

The applications of Western/immunoblotting (WB) techniques have reached multiple layers
of the scientific community and are now considered routine procedures in the field of …

Dysregulation of mRNA translation is a frequent feature of neoplasia. Many oncogenes and
tumour suppressors affect the translation machinery, making aberrant translation a …