Traumatic spinal cord injury results in severe and irreversible loss of function. The injury
triggers a complex cascade of inflammatory and pathological processes, culminating in …

In recent years, the inter-relationship between the innate immune system and the central
nervous system (CNS) has moved to the forefront of biomedical research, with the discovery …

The practical application of nanoparticles (NPs) as chemotherapeutic drug delivery systems
is often hampered by issues such as poor circulation stability and targeting inefficiency …

Neurodegenerative diseases are characterized by neuronal impairment and loss of function,
and with the major shared histopathological hallmarks of misfolding and aggregation of …

Tissue damage can resolve completely through healing and regeneration, or can produce
permanent scarring and loss of function. The response to tissue damage varies across …

Various immune cells and cytokines are present in the aftermath of peripheral nerve injuries
(PNI), and coordination of the local inflammatory response is of great significance for the …

Traumatic brain injury (TBI) is associated with high mortality and disability, with a substantial
socioeconomic burden. With the standardization of the treatment process, there is increasing …

Many people around the world suffer from some form of paralysis caused by spinal cord
injury (SCI), which has an impact on quality and life expectancy. The spinal cord is part of …

Remyelination requires innate immune system function, but how exactly microglia and
macrophages clear myelin debris after injury and tailor a specific regenerative response is …

Microplastics (MPs) are ubiquitous in the environment and pose substantial threats to the
water ecosystem. However, the impact of natural aging of MPs on their toxicity has rarely …