Metagenomic approaches in microbial ecology: an update on whole-genome and marker gene sequencing analyses

AE Pérez-Cobas, L Gomez-Valero… - Microbial …, 2020 - microbiologyresearch.org
Metagenomics and marker gene approaches, coupled with high-throughput sequencing
technologies, have revolutionized the field of microbial ecology. Metagenomics is a culture …

Machine learning approaches in microbiome research: challenges and best practices

G Papoutsoglou, S Tarazona, MB Lopes… - Frontiers in …, 2023 - frontiersin.org
Microbiome data predictive analysis within a machine learning (ML) workflow presents
numerous domain-specific challenges involving preprocessing, feature selection, predictive …

microbiomeMarker: an R/Bioconductor package for microbiome marker identification and visualization

Y Cao, Q Dong, D Wang, P Zhang, Y Liu, C Niu - Bioinformatics, 2022 - academic.oup.com
Characterizing biomarkers based on microbiome profiles has great potential for translational
medicine and precision medicine. Here, we present microbiomeMarker, an R/Bioconductor …

Using MicrobiomeAnalyst for comprehensive statistical, functional, and meta-analysis of microbiome data

J Chong, P Liu, G Zhou, J Xia - Nature protocols, 2020 - nature.com
MicrobiomeAnalyst is an easy-to-use, web-based platform for comprehensive analysis of
common data outputs generated from current microbiome studies. It enables researchers …

[HTML][HTML] Altered mycobiota signatures and enriched pathogenic Aspergillus rambellii are associated with colorectal cancer based on multicohort fecal metagenomic …

Y Lin, HCH Lau, Y Liu, X Kang, Y Wang, NLN Ting… - Gastroenterology, 2022 - Elsevier
Background & Aims The enteric mycobiota is a major component of the human gut
microbiota, but its role in colorectal cancer (CRC) remains largely elusive. We conducted a …

Computational methods for strain-level microbial detection in colony and metagenome sequencing data

C Anyansi, TJ Straub, AL Manson, AM Earl… - Frontiers in …, 2020 - frontiersin.org
Metagenomic sequencing is a powerful tool for examining the diversity and complexity of
microbial communities. Most widely used tools for taxonomic profiling of metagenomic …

Brain tumor detection based on multimodal information fusion and convolutional neural network

M Li, L Kuang, S Xu, Z Sha - IEEE access, 2019 - ieeexplore.ieee.org
Aiming at the problem of low accuracy of traditional brain tumor detection, in this paper, a
combination of multimodal information fusion and convolution neural network detection …

A review of normalization and differential abundance methods for microbiome counts data

D Swift, K Cresswell, R Johnson… - Wiley …, 2023 - Wiley Online Library
The recent development of cost‐effective high‐throughput DNA sequencing technologies
has tremendously increased microbiome research. However, it has been well documented …

Statistical normalization methods in microbiome data with application to microbiome cancer research

Y Xia - Gut Microbes, 2023 - Taylor & Francis
Mounting evidence has shown that gut microbiome is associated with various cancers,
including gastrointestinal (GI) tract and non-GI tract cancers. But microbiome data have …

[HTML][HTML] Recommendations for the introduction of metagenomic next-generation sequencing in clinical virology, part II: bioinformatic analysis and reporting

JJC de Vries, JR Brown, N Couto, M Beer… - Journal of Clinical …, 2021 - Elsevier
Metagenomic next-generation sequencing (mNGS) is an untargeted technique for
determination of microbial DNA/RNA sequences in a variety of sample types from patients …