Reperfusion injury, the paradoxical tissue response that is manifested by blood flow-
deprived and oxygen-starved organs following the restoration of blood flow and tissue …

Byproducts of normal mitochondrial metabolism and homeostasis include the buildup of
potentially damaging levels of reactive oxygen species (ROS), Ca2+, etc., which must be …

Photodynamic therapy (PDT) is a well-established modality for cancer therapy, which locally
kills cancer cells when light irradiates a photosensitizer. However, conventional PDT is often …

Current scientific debates center on the impact of lipids and mitochondrial function on
diverse aspects of human health, nutrition and disease, among them the association of …

Objectives: We investigated the effect of reducing mitochondrial oxidative stress by the
mitochondrial-targeted antioxidant peptide SS-31 in hypertensive cardiomyopathy …

While it is generally accepted that mitochondrial reactive oxygen species (ROS) balance
depends on the both rate of single electron reduction of O2 to superoxide (O2−) by the …

This review highlights the important role of redox signaling between mitochondria and
NADPH oxidases. Besides the definition and general importance of redox signaling, the …

Reduction-oxidation or “redox” reactions are an integral part of a broad range of cellular
processes such as gene expression, energy metabolism, protein import and folding, and …

Cardiac arrhythmias can cause sudden cardiac death (SCD) and add to the current heart
failure (HF) health crisis. Nevertheless, the pathological processes underlying arrhythmias …

The net emission of hydrogen peroxide (H2O2) from mitochondria results from the balance
between reactive oxygen species (ROS) continuously generated in the respiratory chain and …