Laser speckle contrast imaging in biomedical optics

DA Boas, AK Dunn - Journal of biomedical optics, 2010 - spiedigitallibrary.org
First introduced in the 1980s, laser speckle contrast imaging is a powerful tool for full-field
imaging of blood flow. Recently laser speckle contrast imaging has gained increased …

Review of laser speckle contrast techniques for visualizing tissue perfusion

M Draijer, E Hondebrink, T Van Leeuwen… - Lasers in medical …, 2009 - Springer
When a diffuse object is illuminated with coherent laser light, the backscattered light will form
an interference pattern on the detector. This pattern of bright and dark areas is called a …

Dynamic light scattering imaging

DD Postnov, J Tang, SE Erdener, K Kılıç, DA Boas - Science advances, 2020 - science.org
We introduce dynamic light scattering imaging (DLSI) to enable the wide-field measurement
of the speckle temporal intensity autocorrelation function. DLSI uses the full temporal …

Detrimental effects of speckle-pixel size matching in laser speckle contrast imaging

SJ Kirkpatrick, DD Duncan, EM Wells-Gray - Optics letters, 2008 - opg.optica.org
Through a series of simulations and experiments, we demonstrate that the frequently cited
criterion of matching speckle size to detector element (pixel) size in laser speckle contrast …

Can laser speckle flowmetry be made a quantitative tool?

DD Duncan, SJ Kirkpatrick - JOSA A, 2008 - opg.optica.org
The ultimate objective of laser speckle flowmetry (and a host of specific implementations
such as laser speckle contrast analysis, LASCA or LSCA; laser speckle spatial contrast …

Laser speckle imaging to monitor microvascular blood flow: a review

PG Vaz, A Humeau-Heurtier, E Figueiras… - IEEE reviews in …, 2016 - ieeexplore.ieee.org
Laser speckle is a complex interference phenomenon that can easily be understood, in
concept, but is difficult to predict mathematically, because it is a stochastic process. The use …

Review of laser speckle-based analysis in medical imaging

K Basak, M Manjunatha, PK Dutta - Medical & biological engineering & …, 2012 - Springer
Speckle pattern forms when a rough object is illuminated with coherent light (laser) and the
backscattered radiation is imaged on a screen. The pattern changes over time due to …

Comparison of laser speckle contrast imaging with laser Doppler for assessing microvascular function

GA Tew, M Klonizakis, H Crank, JD Briers… - Microvascular …, 2011 - Elsevier
OBJECTIVE: To compare the inter-day reproducibility of post-occlusive reactive hyperaemia
(PORH) and sympathetic vasomotor reflexes assessed by single-point laser Doppler …

Intraoperative laser speckle contrast imaging for real-time visualization of cerebral blood flow in cerebrovascular surgery: results from pre-clinical studies

A Mangraviti, F Volpin, J Cha, SI Cunningham… - Scientific reports, 2020 - nature.com
Cerebrovascular surgery can benefit from an intraoperative system that conducts continuous
monitoring of cerebral blood flow (CBF). Such a system must be handy, non-invasive, and …

Temporal statistical analysis of laser speckle images and its application to retinal blood-flow imaging

H Cheng, Y Yan, TQ Duong - Optics express, 2008 - opg.optica.org
Temporal-statistical analysis of laser-speckle image (TS-LSI) preserves the original spatial
resolution, in contrast to conventional spatial-statistical analysis (SS-LSI). Concerns have …