Atherosclerosis is a chronic inflammatory disease, in which the immune system has a
prominent role in its development and progression. Inflammation-induced endothelial …

Cardiac injury remains a major cause of morbidity and mortality worldwide. Despite
significant advances, a full understanding of why the heart fails to fully recover function after …

The immune system is fundamental to tissue homeostasis and is the first line of defense
following infection, injury or disease. In the damaged heart, large numbers of immune cells …

Coronary microvascular dysfunction (CMD) is related to a broad variety of clinical scenarios
in which cardiac microvasculature is morphologically and functionally affected, and it is …

There are currently no approved pharmacological treatment options for aortic stenosis (AS),
and there are limited identified drug targets for this chronic condition. It remains unclear …

The incidence of heart failure with preserved ejection fraction is increasing in patients with
obesity, diabetes, hypertension, and in the aging population. However, there is a lack of …

Background Low-dose colchicine significantly reduces the risk of cardiovascular events in
patients with chronic coronary disease. An increase of non-cardiovascular death raised …

Several lines of evidence have clearly indicated that inflammation plays a pivotal role in the
development of atherosclerosis and of its thrombotic complications such as acute coronary …

Colchicine for the secondary prevention of cardiovascular events - PMC Back to Top Skip to
main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content …

Inflammation is a key feature of atherosclerosis. The inflammatory process is involved in all
stages of disease progression, from the early formation of plaque to its instability and …