Histotripsy: the first noninvasive, non-ionizing, non-thermal ablation technique based on ultrasound
Z Xu, TL Hall, E Vlaisavljevich… - International Journal of …, 2021 - Taylor & Francis
Histotripsy is the first noninvasive, non-ionizing, and non-thermal ablation technology
guided by real-time imaging. Using focused ultrasound delivered from outside the body …
guided by real-time imaging. Using focused ultrasound delivered from outside the body …
[HTML][HTML] For whom the bubble grows: physical principles of bubble nucleation and dynamics in histotripsy ultrasound therapy
Histotripsy is a focused ultrasound therapy for non-invasive tissue ablation. Unlike thermally
ablative forms of therapeutic ultrasound, histotripsy relies on the mechanical action of …
ablative forms of therapeutic ultrasound, histotripsy relies on the mechanical action of …
Histotripsy: a method for mechanical tissue ablation with ultrasound
Z Xu, TD Khokhlova, CS Cho… - Annual Review of …, 2024 - annualreviews.org
Histotripsy is a relatively new therapeutic ultrasound technology to mechanically liquefy
tissue into subcellular debris using high-amplitude focused ultrasound pulses. In contrast to …
tissue into subcellular debris using high-amplitude focused ultrasound pulses. In contrast to …
Effects of ultrasound frequency and tissue stiffness on the histotripsy intrinsic threshold for cavitation
Histotripsy is an ultrasound ablation method that depends on the initiation of a cavitation
bubble cloud to fractionate soft tissue. Previous work has indicated that a cavitation cloud …
bubble cloud to fractionate soft tissue. Previous work has indicated that a cavitation cloud …
The histotripsy spectrum: differences and similarities in techniques and instrumentation
RP Williams, JC Simon, VA Khokhlova… - International Journal …, 2023 - Taylor & Francis
Since its inception about two decades ago, histotripsy–a non-thermal mechanical tissue
ablation technique–has evolved into a spectrum of methods, each with distinct potentiating …
ablation technique–has evolved into a spectrum of methods, each with distinct potentiating …
Sonoelastomics for breast tumor classification: a radiomics approach with clustering-based feature selection on sonoelastography
A radiomics approach to sonoelastography, called “sonoelastomics,” is proposed for
classification of benign and malignant breast tumors. From sonoelastograms of breast …
classification of benign and malignant breast tumors. From sonoelastograms of breast …
Deep laser microscopy using optical clearing by ultrasound-induced gas bubbles
Although laser scanning microscopy is a pivotal imaging tool in biomedical research, optical
scattering from tissue limits the depth of the imaging. To overcome this limitation, we …
scattering from tissue limits the depth of the imaging. To overcome this limitation, we …
Ultrasound-guided noninvasive pancreas ablation using histotripsy: feasibility study in an in vivo porcine model
Pancreatic cancer is a malignant disease associated with poor survival and nearly 80%
present with unresectable tumors. Treatments such as chemotherapy and radiation therapy …
present with unresectable tumors. Treatments such as chemotherapy and radiation therapy …
[HTML][HTML] Numerical investigation of the inertial cavitation threshold under multi-frequency ultrasound
Through the introduction of multi-frequency sonication in High Intensity Focused Ultrasound
(HIFU), enhancement of efficiency has been noted in several applications including …
(HIFU), enhancement of efficiency has been noted in several applications including …
Histotripsy ablation of spontaneously occurring canine bone tumors
Objective: Osteosarcoma (OS) is a devastating primary bone tumor in dogs and humans with
limited non-surgical treatment options. As the first completely non-invasive and non-thermal …
limited non-surgical treatment options. As the first completely non-invasive and non-thermal …