Abstract Helicobacter pylori (H. pylori), discovered in 1982, is a microaerophilic, spiral-
shaped gram-negative bacterium that is able to colonize the human stomach. Nearly half of …

Helicobacter pylori is now well known as an important pathogen related to the development
of gastric cancer. However, some clinicians still doubt the causal association of H. pylori with …

Background Interleukin-1 beta (IL-1β), a pro-inflammatory cytokine, is emerging as a key
mediator of carcinogenesis that characterizes host-environment interactions …

Abstract Background and Aim: We aimed to explore the role of interleukin (IL)‐1B cluster
gene polymorphisms at positions− 511,− 31, and+ 3954 and the receptor IL‐1RN variable …

Background The association between proinflammatory cytokine gene polymorphisms and
gastric diseases related to Helicobacter pylori varies by population and geographic area …

Helicobacter pylori (H. pylori) infection is the most common chronic bacterial infection in the
world and the etiological agent for most gastric cancer (GC). Interleukin-1β (IL-1β) is a potent …

Methods To obtain a maximum number of articles, an extensive electronic search of the
literature was conducted in the PubMed MEDLINE and Cochrane Library databases …

Objective Oxidative stress caused by the pro-inflammatory cytokine interleukin (IL)-1β has
been widely investigated for cancer risk. In this study, we focused on the role of IL-1β …

(1) Background: Saudi Arabia (SA) is a country with a low incidence of gastric cancer (GC).
In this study, we sought to assess the epidemiology of GC, its clinicopathological profiles …

Background Gastric cancer is one of the most common malignancies afflicting the Chinese
population. Polymorphisms in interleukin-1B (IL-1B) and interleukin-1 receptor antagonist (IL …