Liver fibrosis: a compilation on the biomarkers status and their significance during disease progression

KS Nallagangula, SK Nagaraj, L Venkataswamy… - Future science …, 2018 - Taylor & Francis
Liver fibrosis occurs in response to different etiologies of chronic liver injury. Diagnosing
degree of liver fibrosis is a crucial step in evaluation of severity of the disease. An invasive …

Metabolic signature of hepatic fibrosis: from individual pathways to systems biology

ML Chang, SS Yang - Cells, 2019 - mdpi.com
Hepatic fibrosis is a major cause of morbidity and mortality worldwide, as it ultimately leads
to cirrhosis, which is estimated to affect up to 2% of the global population. Hepatic fibrosis is …

Noninvasive proteomic biomarkers for alcohol-related liver disease

L Niu, M Thiele, PE Geyer, DN Rasmussen… - Nature Medicine, 2022 - nature.com
Alcohol-related liver disease (ALD) is a major cause of liver-related death worldwide, yet
understanding of the three key pathological features of the disease—fibrosis, inflammation …

Human hepatic gene expression signature of non-alcoholic fatty liver disease progression, a meta-analysis

M Ryaboshapkina, M Hammar - Scientific reports, 2017 - nature.com
Non-alcoholic fatty liver disease (NAFLD) is a wide-spread chronic liver condition that
places patients at risk of developing cardiovascular diseases and may progress to cirrhosis …

Lipids and HCV

MF Bassendine, DA Sheridan, SH Bridge… - Seminars in …, 2013 - Springer
Chronic hepatitis C virus (HCV) infection is associated with an increase in hepatic steatosis
and a decrease in serum levels of total cholesterol, low-density lipoprotein cholesterol (LDL) …

[HTML][HTML] The platelet-to-lymphocyte ratio, superior to the neutrophil-to-lymphocyte ratio, correlates with hepatitis C virus infection

X Meng, G Wei, Q Chang, R Peng, G Shi… - International Journal of …, 2016 - Elsevier
Objectives The platelet-to-lymphocyte ratio (PLR) and neutrophil-to-lymphocyte ratio (NLR)
have been studied widely in cancer diseases. However, their correlation with hepatitis C …

[HTML][HTML] Non-invasive assessment of liver fibrosis: Between prediction/prevention of outcomes and cost-effectiveness

C Stasi, S Milani - World journal of gastroenterology, 2016 - ncbi.nlm.nih.gov
The assessment of the fibrotic evolution of chronic hepatitis has always been a challenge for
the clinical hepatologist. Over the past decade, various non-invasive methods have been …

[HTML][HTML] Epigenetic signatures of alcohol abuse and hepatitis infection during human hepatocarcinogenesis

RA Hlady, RL Tiedemann, W Puszyk, I Zendejas… - Oncotarget, 2014 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the second most common cause of cancer deaths
worldwide. Deregulated DNA methylation landscapes are ubiquitous in human cancers …

A high-density lipoprotein-mediated drug delivery system

ZC Mo, K Ren, X Liu, ZL Tang, GH Yi - Advanced drug delivery reviews, 2016 - Elsevier
High-density lipoprotein (HDL) is a comparatively dense and small lipoprotein that can carry
lipids as a multifunctional aggregate in plasma. Several studies have shown that increasing …

Alpha-fetoprotein level as a biomarker of liver fibrosis status: a cross-sectional study of 619 consecutive patients with chronic hepatitis B

Y Liu, B Lin, D Zeng, Y Zhu, J Chen, Q Zheng… - BMC …, 2014 - Springer
Abstract Background Hepatitis B virus (HBV) infection is a serious public health problem
worldwide. This study aimed to investigate the relationship between serum alpha-fetoprotein …