Cerebral oxygen extraction fraction MRI: Techniques and applications

D Jiang, H Lu - Magnetic resonance in medicine, 2022 - Wiley Online Library
The human brain constitutes 2% of the body's total mass but uses 20% of the oxygen. The
rate of the brain's oxygen utilization can be derived from a knowledge of cerebral blood flow …

[HTML][HTML] A robust multi-scale approach to quantitative susceptibility mapping

J Acosta-Cabronero, C Milovic, H Mattern, C Tejos… - Neuroimage, 2018 - Elsevier
Abstract Quantitative Susceptibility Mapping (QSM), best known as a surrogate for tissue
iron content, is becoming a highly relevant MRI contrast for monitoring cellular and vascular …

Cerebral oxygen extraction fraction (OEF): Comparison of challenge-free gradient echo QSM+qBOLD (QQ) with 15O PET in healthy adults

J Cho, J Lee, H An, MS Goyal, Y Su… - Journal of Cerebral …, 2021 - journals.sagepub.com
We aimed to validate oxygen extraction fraction (OEF) estimations by quantitative
susceptibility mapping plus quantitative blood oxygen-level dependence (QSM+ qBOLD, or …

[HTML][HTML] Brain imaging biomarkers of carotid artery disease

H Baradaran, A Gupta - Annals of translational medicine, 2020 - ncbi.nlm.nih.gov
Extracranial carotid artery atherosclerotic disease is a major contributor to ischemic stroke.
Carotid atherosclerotic disease can present with a spectrum of findings ranging from mild …

Cerebral metabolic rate of oxygen (CMRO2) mapping by combining quantitative susceptibility mapping (QSM) and quantitative blood oxygenation level‐dependent …

J Cho, Y Kee, P Spincemaille… - Magnetic resonance …, 2018 - Wiley Online Library
Purpose To map the cerebral metabolic rate of oxygen (CMRO2) by estimating the oxygen
extraction fraction (OEF) from gradient echo imaging (GRE) using phase and magnitude of …

Quantitative susceptibility mapping (QSM) algorithms: mathematical rationale and computational implementations

Y Kee, Z Liu, L Zhou, A Dimov, J Cho… - IEEE Transactions …, 2017 - ieeexplore.ieee.org
Quantitative susceptibility mapping (QSM) solves the magnetic field-to-magnetization (tissue
susceptibility) inverse problem under conditions of noisy and incomplete field data acquired …

Cluster analysis of time evolution (CAT) for quantitative susceptibility mapping (QSM) and quantitative blood oxygen level‐dependent magnitude (qBOLD)‐based …

J Cho, S Zhang, Y Kee, P Spincemaille… - Magnetic resonance …, 2020 - Wiley Online Library
Purpose To improve the accuracy of QSM plus quantitative blood oxygen level‐dependent
magnitude (QSM+ qBOLD or QQ)‐based mapping of the oxygen extraction fraction (OEF) …

[HTML][HTML] Initial experience of challenge-free MRI-based oxygen extraction fraction mapping of ischemic stroke at various stages: comparison with perfusion and …

S Zhang, J Cho, TD Nguyen, P Spincemaille… - Frontiers in …, 2020 - frontiersin.org
MRI-based oxygen extraction fraction imaging has a great potential benefit in the selection
of clinical strategies for ischemic stroke patients. This study aimed to evaluate the …

Brain oxygen extraction fraction mapping in patients with multiple sclerosis

J Cho, TD Nguyen, W Huang… - Journal of Cerebral …, 2022 - journals.sagepub.com
We aimed to demonstrate the feasibility of whole brain oxygen extraction fraction (OEF)
mapping for measuring lesion specific and regional OEF abnormalities in multiple sclerosis …

System and method of robust quantitative susceptibility mapping

Y Wang, Z Liu, Y Kee, A Dimov, Y Wen… - US Patent …, 2021 - Google Patents
2018-09-27 Assigned to CORNELL UNIVERSITY reassignment CORNELL UNIVERSITY
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …