The biologically relevant coordination chemistry of iron and nitric oxide: electronic structure and reactivity

N Lehnert, E Kim, HT Dong, JB Harland… - Chemical …, 2021 - ACS Publications
Nitric oxide (NO) is an important signaling molecule that is involved in a wide range of
physiological and pathological events in biology. Metal coordination chemistry, especially …

Protein S-nitrosylation: determinants of specificity and enzymatic regulation of S-nitrosothiol-based signaling

CT Stomberski, DT Hess, JS Stamler - Antioxidants & redox …, 2019 - liebertpub.com
Significance: Protein S-nitrosylation, the oxidative modification of cysteine by nitric oxide
(NO) to form protein S-nitrosothiols (SNOs), mediates redox-based signaling that conveys, in …

Living/controlled anionic polymerization of glycolide in fluoroalcohols: toward sustainable bioplastics

P Zhang, V Ladelta… - Journal of the American …, 2023 - ACS Publications
Ring-opening polymerization (ROP) is a promising approach to accessing well-defined
polyesters with superior (bio) degradability and recyclability. However, the living/controlled …

Small molecule signaling agents: the integrated chemistry and biochemistry of nitrogen oxides, oxides of carbon, dioxygen, hydrogen sulfide, and their derived …

JM Fukuto, SJ Carrington, DJ Tantillo… - Chemical research in …, 2012 - ACS Publications
Several small molecule species formally known primarily as toxic gases have, over the past
20 years, been shown to be endogenously generated signaling molecules. The biological …

Chemical basis of inflammation-induced carcinogenesis

H Ohshima, M Tatemichi, T Sawa - Archives of biochemistry and biophysics, 2003 - Elsevier
Chronic inflammation induced by biological, chemical, and physical factors has been
associated with increased risk of human cancer at various sites. Inflammation activates a …

Mechanistic aspects of the reactions of nitric oxide with transition-metal complexes

PC Ford, IM Lorkovic - Chemical reviews, 2002 - ACS Publications
It is now well established that nitric oxide (aka nitrogen monoxide) plays fundamental roles
in biochemical processes. 1, 2 Early concerns with the biology of NO were largely focused …

Aging and genome maintenance: lessons from the mouse?

P Hasty, J Campisi, J Hoeijmakers, H Van Steeg, J Vijg - Science, 2003 - science.org
Recent progress in the science of aging is driven largely by the use of model systems,
ranging from yeast and nematodes to mice. These models have revealed conservation in …

Nitroxyl and its anion in aqueous solutions: spin states, protic equilibria, and reactivities toward oxygen and nitric oxide

V Shafirovich, SV Lymar - Proceedings of the National …, 2002 - National Acad Sciences
The thermodynamic properties of aqueous nitroxyl (HNO) and its anion (NO−) have been
revised to show that the ground state of NO− is triplet and that HNO in its singlet ground state …

The reduction potential of nitric oxide (NO) and its importance to NO biochemistry

MD Bartberger, W Liu, E Ford… - Proceedings of the …, 2002 - National Acad Sciences
A potential of about− 0.8 (±0.2) V (at 1 M versus normal hydrogen electrode) for the
reduction of nitric oxide (NO) to its one-electron reduced species, nitroxyl anion (3NO−) has …

The chemistry of nitroxyl (HNO) and implications in biology

KM Miranda - Coordination Chemistry Reviews, 2005 - Elsevier
Over the past century, HNO research has evolved from fundamental physical examinations
to elucidation of interactions in atmospheric, industrial and bacterial processes. Most …