Isoindolinone Synthesis via One‐Pot Type Transition Metal Catalyzed C− C Bond Forming Reactions

R Savela, C Méndez‐Gálvez - Chemistry–A European Journal, 2021 - Wiley Online Library
Isoindolinone structure is an important privileged scaffold found in a large variety of naturally
occurring as well as synthetic, biologically and pharmaceutically active compounds. Owing …

Aldo‐X Bifunctional Building Blocks for the Synthesis of Heterocycles

P Ravichandiran, B Lai, Y Gu - The Chemical Record, 2017 - Wiley Online Library
Compounds containing oxygen, nitrogen, or sulfur atoms inside the rings are attracting much
attention and interest due to their biological importance. In recent years, several methods for …

Ruthenium-catalyzed redox-neutral [4+ 1] annulation of benzamides and propargyl alcohols via C–H bond activation

X Wu, B Wang, S Zhou, Y Zhou, H Liu - ACS Catalysis, 2017 - ACS Publications
Internal alkynes have been used widely in transition-metal-catalyzed cycloaddition
reactions, in which they generally serve as two-carbon reaction partners. Herein, we report …

Propargyl alcohols as one-carbon synthons: redox-neutral rhodium (III)-catalyzed C–H bond activation for the synthesis of isoindolinones bearing a quaternary carbon

X Wu, B Wang, Y Zhou, H Liu - Organic letters, 2017 - ACS Publications
Herein, rhodium (III)-catalyzed C–H activation/subsequent [4+ 1] cyclization reactions
between benzamides and propargyl alcohols are reported in which propargyl alcohols serve …

Efficient Heterogeneous CO2 to CO Conversion with a Phosphonic Acid Fabricated Cofacial Iron Porphyrin Dimer

EA Mohamed, ZN Zahran, Y Naruta - Chemistry of Materials, 2017 - ACS Publications
For developing renewable fuels and controlling global warming, catalyst promoted
conversion of CO2 to CO is essential. Numerous CO2 to CO conversion molecular catalysts …

Palladium-Catalyzed Unimolecular Fragment Coupling of N-Allylamides via Elimination of Isocyanate

R Shimazumi, R Tanimoto, T Kodama… - Journal of the American …, 2022 - ACS Publications
Transition metal-catalyzed unimolecular fragment coupling (UFC) is defined as processes
that forge new chemical bonds through the extrusion of molecules, such as CO and CO2 …

Enantioselective Hydrophosphonylation of in Situ Generated N-Acyl Ketimines Catalyzed by BINOL-Derived Phosphoric Acid

A Suneja, RA Unhale, VK Singh - Organic letters, 2017 - ACS Publications
An efficient route to pharmacologically interesting isoindolinone-based α-amino
phosphonates is described via asymmetric hydrophosphonylation of in situ generated …

Zn-mediated electrochemical α-alkylation of amines with halogenated alkanes through convergent paired electrolysis

X Zhan, H Liu, R Liu, Y Huang, Y Peng - Green Chemistry, 2023 - pubs.rsc.org
Herein, we report a green and sustainable electrochemical strategy for α-alkylation of tertiary
amines with halogenated alkanes under undivided electrolytic conditions. A Barbier …

Continuous and selective hydrogenation of heterocyclic nitroaromatics in a micropacked bed reactor

X Duan, X Wang, X Chen, J Zhang - Organic Process Research & …, 2021 - ACS Publications
The hydrogenation of heterocyclic nitroaromatics is of great importance in the
pharmaceutical industry for the synthesis of key intermediates. However, high selectivity is …

Isoindolinone synthesis: selective dioxane-mediated aerobic oxidation of isoindolines

P Thapa, E Corral, S Sardar, BS Pierce… - The Journal of Organic …, 2018 - ACS Publications
N-Alkyl and N-aryl-isoindolinones were prepared by a dioxane-mediated oxidation of
isoindoline precursors. The transformation exhibits unique chemoselectivity for …