Omega-3 long-chain polyunsaturated fatty acids: Metabolism and health implications

I Khan, M Hussain, B Jiang, L Zheng, Y Pan, J Hu… - Progress in lipid …, 2023 - Elsevier
Abstract Recently, omega-3 long-chain polyunsaturated fatty acids (n-3 LC-PUFAs) have
gained substantial interest due to their specific structure and biological functions. Humans …

Omega-3 polyunsaturated fatty acids and cancer: lessons learned from clinical trials

SF Nabavi, S Bilotto, GL Russo, IE Orhan… - Cancer and Metastasis …, 2015 - Springer
Over the past decades, extensive studies have addressed the therapeutic effects of omega-3
polyunsaturated fatty acids (omega-3 FAs) against different human diseases such as …

Potential applications of fish oils rich in omega-3 polyunsaturated fatty acids in the management of gastrointestinal cancer

AM Eltweri, AL Thomas, M Metcalfe, PC Calder… - Clinical nutrition, 2017 - Elsevier
Background & aims Despite advances in chemotherapeutic agents and surgical approaches
for its management, gastrointestinal cancer still accounts for 27% of new cancer cases and …

Docosahexaenoic acid: a natural powerful adjuvant that improves efficacy for anticancer treatment with no adverse effects

RA Siddiqui, KA Harvey, Z Xu, EM Bammerlin… - Biofactors, 2011 - Wiley Online Library
Epidemiological studies have linked fish oil consumption to a decreased incidence of
cancer. The anticancer effects of fish oil are mostly attributed to its content of omega‐3 fatty …

Docosahexaenoic acid–mediated, targeted and sustained brain delivery of curcumin microemulsion

RL Shinde, PV Devarajan - Drug delivery, 2017 - Taylor & Francis
We disclose microemulsions (ME) of curcumin (CUR) with docosahexaenoic acid (DHA)-rich
oil (CUR DHA ME) for targeted delivery to the brain. MEs of CUR (5 mg/mL) with and without …

Omega-3 fatty acids, membrane remodeling and cancer prevention

NR Fuentes, E Kim, YY Fan, RS Chapkin - Molecular aspects of medicine, 2018 - Elsevier
Proteins are often credited as the macromolecule responsible for performing critical cellular
functions, however lipids have recently garnered more attention as our understanding of …

Selective sensitization of tumors to chemotherapy by marine-derived lipids: a review

N Hajjaji, P Bougnoux - Cancer treatment reviews, 2013 - Elsevier
Despite great improvements, a significant proportion of cancer patients still die, mainly
because of the development of metastases. At this stage, current treatments still rely heavily …

Anti-inflammatory effects of docosahexaenoic acid: Implications for its cancer chemopreventive potential

HW Yum, HK Na, YJ Surh - Seminars in Cancer Biology, 2016 - Elsevier
The implication of inflammatory tissue damage in pathophysiology of human cancer as well
as some metabolic disorders has been under intense investigation. Numerous studies have …

Colon cancer cell chemosensitisation by fish oil emulsion involves apoptotic mitochondria pathway

V Granci, F Cai, E Lecumberri, A Clerc… - British journal of …, 2013 - cambridge.org
Adjuvant use of safe compounds with anti-tumour properties has been proposed to improve
cancer chemotherapy outcome. We aimed to investigate the effects of fish oil emulsion …

Lipid-lowering drugs and cancer: an updated perspective

A Alizadehasl, MS Alavi, S Boudagh, MS Alavi… - Pharmacological …, 2024 - Springer
Statins and non-statin medications used for the management of dyslipidemia have been
shown to possess antitumor properties. Since the use of these drugs has steadily increased …