The longstanding focus in chronic kidney disease (CKD) research has been on the
glomerulus, which is sensible because this is where glomerular filtration occurs, and a large …

Although kidney transplantation has been an important means for the treatment of patients
with end stage of renal disease, the long-term survival rate of the renal allograft remains a …

Many complications after renal transplantation can be prevented if they are detected early.
Guidelines have been developed for the prevention of diseases in the general population …

Identifying factors that are predictive of allograft loss might be an important step toward
prolonging kidney allograft survival. In this study we sought to determine the association …

Chronic allograft nephropathy (CAN) in protocol biopsies is associated with graft loss while
the association between subclinical rejection (SCR) and outcome has yielded contradictory …

Background. Clinical trials in renal transplantation must use surrogate markers of long-term
graft survival if conclusions are to be drawn at acceptable speed and cost. Morphologic …

Chronic allograft nephropathy (CAN) is due to both immunologic and non-immunologic
factors and results in the development of nonspecific pathologic features that may even be …

Risk factors for chronic allograft nephropathy after renal transplantation: A protocol biopsy
study. Background Chronic allograft nephropathy (CAN) leads to chronic allograft …

Subclinical rejection (SCR) of renal allografts refers to histologic patterns of acute rejection
despite stable renal function. The clinical approach to SCR is controversial; it would be …

This study is an investigation of whether a protocol biopsy may be used as surrogate to late
graft survival in multicenter renal transplantation trials. During two mycophenolate mofetil …