Neuroendocrine tumor biomarkers: From monoanalytes to transcripts and algorithms
IM Modlin, L Bodei, M Kidd - … practice & research Clinical endocrinology & …, 2016 - Elsevier
The management of neuroendocrine neoplasia remains a perplexing problem because of
the lack of knowledge of the biology of the disease, its late presentation, the relative …
the lack of knowledge of the biology of the disease, its late presentation, the relative …
Neuroendocrine tumor biomarkers: current status and perspectives
The identification of accurate harbingers of disease status and therapeutic efficacy are
critical requirements in precise diagnosis and effective management. Initially, tissue analysis …
critical requirements in precise diagnosis and effective management. Initially, tissue analysis …
The emerging roles of chromogranins and derived polypeptides in atherosclerosis, diabetes, and coronary heart disease
T Watanabe - International Journal of Molecular Sciences, 2021 - mdpi.com
Chromogranin A (CgA), B (CgB), and C (CgC), the family members of the granin
glycoproteins, are associated with diabetes. These proteins are abundantly expressed in …
glycoproteins, are associated with diabetes. These proteins are abundantly expressed in …
Granin-derived peptides
The granin family comprises altogether 7 different proteins originating from the diffuse
neuroendocrine system and elements of the central and peripheral nervous systems. The …
neuroendocrine system and elements of the central and peripheral nervous systems. The …
Chromogranin A regulation of obesity and peripheral insulin sensitivity
GK Bandyopadhyay, SK Mahata - Frontiers in Endocrinology, 2017 - frontiersin.org
Chromogranin A (CgA) is a prohormone and granulogenic factor in endocrine and
neuroendocrine tissues, as well as in neurons, and has a regulated secretory pathway. The …
neuroendocrine tissues, as well as in neurons, and has a regulated secretory pathway. The …
Chromogranin A and its role in the pathogenesis of diabetes mellitus
Z Herold, M Doleschall, A Kovesdi… - Endokrynologia …, 2018 - journals.viamedica.pl
Chromogranin A is a member of the granin glycoprotein family that is expressed by the
endocrine and neuroendocrine cells of different organs. Intracellularly, chromogranin A …
endocrine and neuroendocrine cells of different organs. Intracellularly, chromogranin A …
Chromogranins: from discovery to current times
KB Helle, MH Metz-Boutigue, MC Cerra… - Pflügers Archiv-European …, 2018 - Springer
The discovery in 1953 of the chromaffin granules as co-storage of catecholamines and ATP
was soon followed by identification of a range of uniquely acidic proteins making up the …
was soon followed by identification of a range of uniquely acidic proteins making up the …
Discovery of pancreastatin inhibitor PSTi8 for the treatment of insulin resistance and diabetes: studies in rodent models of diabetes mellitus
Pancreastatin (PST) is an endogenous peptide which regulates glucose and lipid
metabolism in liver and adipose tissues. In type 2 diabetic patients, PST level is high and …
metabolism in liver and adipose tissues. In type 2 diabetic patients, PST level is high and …
Chromogranin-A and its derived peptides and their pharmacological effects during intestinal inflammation
The gastrointestinal tract is the largest endocrine organ that produces a broad range of
active peptides. Mucosal changes during inflammation alter the distribution and products of …
active peptides. Mucosal changes during inflammation alter the distribution and products of …
Chromogranin A and its derived peptides: potential regulators of cholesterol homeostasis
DR Iyer, J Venkatraman, E Tanguy, N Vitale… - Cellular and Molecular …, 2023 - Springer
Chromogranin A (CHGA), a member of the granin family of proteins, has been an attractive
therapeutic target and candidate biomarker for several cardiovascular, neurological, and …
therapeutic target and candidate biomarker for several cardiovascular, neurological, and …