Contact lenses: promising devices for ocular drug delivery

A Guzman-Aranguez, B Colligris… - Journal of ocular …, 2013 - liebertpub.com
In the ocular pharmacology market, there is a noteworthy unmet demand for more
efficacious delivery of ocular therapeutics. Contact lenses are emerging as an alternative …

Commercialization challenges for drug eluting contact lenses

OL Lanier, KG Christopher, RM Macoon… - Expert Opinion on …, 2020 - Taylor & Francis
Introduction Eye drops are commonly used for delivering ophthalmic drugs despite many
deficiencies including low bioavailability and poor compliance. Contact lenses can deliver …

BCLA CLEAR-Contact lens complications

F Stapleton, M Bakkar, N Carnt, R Chalmers… - Contact Lens and …, 2021 - Elsevier
Contact lens-related complications are common, affecting around one third of wearers,
although most are mild and easily managed. Contact lenses have well-defined anatomical …

BCLA CLEAR-evidence-based contact lens practice

JS Wolffsohn, K Dumbleton, B Huntjens… - Contact Lens and …, 2021 - Elsevier
Evidence-based contact lens practice involves finding, appraising and applying research
findings as the basis for patient management decisions. These decisions should be …

[HTML][HTML] The TFOS International Workshop on Contact Lens Discomfort: report of the contact lens interactions with the ocular surface and adnexa subcommittee

N Efron, L Jones, AJ Bron, E Knop… - … & visual science, 2013 - tvst.arvojournals.org
The report of this subcommittee concerns the impact of contact lenses (CLs) on the ocular
surface, with a particular emphasis on CL discomfort (CLD). We define the ocular surface, its …

TREM-2 promotes host resistance against Pseudomonas aeruginosa infection by suppressing corneal inflammation via a PI3K/Akt signaling pathway

M Sun, M Zhu, K Chen, X Nie, Q Deng… - … & visual science, 2013 - iovs.arvojournals.org
Purpose.: To explore the role of triggering receptor expressed on myeloid cells 2 (TREM-2)
in Pseudomonas aeruginosa (PA) keratitis. Methods.: BALB/c mice were routinely infected …

Three-year follow-up of secondary anterior iris fixation of an aphakic intraocular lens to correct aphakia

Y Chen, Q Liu, C Xue, Z Huang… - Journal of Cataract & …, 2012 - journals.lww.com
Three-year follow-up of secondary anterior iris fixation of... : Journal of Cataract & Refractive
Surgery Three-year follow-up of secondary anterior iris fixation of an aphakic intraocular lens …

Mechanical complications induced by silicone hydrogel contact lenses

MC Lin, TN Yeh - Eye & contact lens, 2013 - journals.lww.com
With the introduction of silicone hydrogel (SiHy) lenses over a decade ago, clinicians have
seen both improvements and challenges in contact lens (CL) wear. Regardless of lens …

Imprinted hydrogels with LbL coating for dual drug release from soft contact lenses materials

D Silva, HC de Sousa, MH Gil, LF Santos… - Materials Science and …, 2021 - Elsevier
A combined strategy to control the release of two drugs, one anti-inflammatory (diclofenac
sodium, DCF) and one antibiotic (moxifloxacin hydrochloride, MXF), from a soft contact lens …

Tear proteases and protease inhibitors: potential biomarkers and disease drivers in ocular surface disease

R Fu, W Klinngam, M Heur, MC Edman… - Eye & contact …, 2020 - journals.lww.com
Tears are highly concentrated in proteins relative to other biofluids, and a notable fraction of
tear proteins are proteases and protease inhibitors. These components are present in a …