Epithelial cells repress epithelial characteristics and elaborate mesenchymal characteristics
to migrate to other locations and acquire new properties. Epithelial plasticity responses are …

Simple Summary The epithelial to mesenchymal transition (EMT) is a well-documented
process in the study of cancer metastases. The cytoskeleton is an intricate network involved …

The epithelial-to-mesenchymal transition, which conveys epithelial (E) carcinoma cells to
quasi-mesenchymal (qM) states, enables them to metastasize and acquire resistance to …

Cancer stem cells (CSCs) may serve as the cellular seeds of tumor recurrence and
metastasis, and they can be generated via epithelial-mesenchymal transitions (EMTs) …

Morphological transitions are typically attributed to the actions of proteins and lipids. Largely
overlooked in membrane shape regulation is the glycocalyx, a pericellular membrane coat …

The adenoma-to-carcinoma progression in colon cancer is driven by a sequential
accumulation of genetic alterations at specific tumor suppressors and oncogenes. In …

Ezrin is the cytoskeletal organizer and functions in the modulation of membrane–
cytoskeleton interaction, maintenance of cell shape and structure, and regulation of cell–cell …

Cancer metastasis is the primary cause of morbidity and mortality in cancer as it remains the
most complicated, devastating, and enigmatic aspect of cancer. Several decades of …

Podocalyxin (PODXL) overexpression is associated with poor clinical outcomes in various
tumors. PODXL is involved in tumor malignant progression through the promotion of …

Emerging microfluidic disease models have amply demonstrated their value in many fields
of cancer research. These in vitro technologies recapitulate key aspects of metastatic …