Role of the bed nucleus of the stria terminalis in aversive learning and memory

TD Goode, S Maren - Learning & Memory, 2017 - learnmem.cshlp.org
Surviving threats in the environment requires brain circuits for detecting (or anticipating)
danger and for coordinating appropriate defensive responses (eg, increased cardiac output …

Targeting neuronal nitric oxide synthase and the nitrergic system in post-traumatic stress disorder

MA Sadeghi, S Hemmati, E Nassireslami… - …, 2022 - Springer
Rationale Current pharmacological approaches to treatment of post-traumatic stress
disorder (PTSD) lack adequate effectiveness. As a result, identifying new molecular targets …

A sex-specific role for the bed nucleus of the stria terminalis in proactive defensive behavior

DP Guerra, W Wang, KA Souza… - …, 2023 - nature.com
The bed nucleus of the stria terminalis (BNST) is a forebrain region implicated in aversive
responses to uncertain threat. Much of the work on the role of BNST in defensive behavior …

Nitric Oxide (NO) Synthase Inhibitors: Potential Candidates for the Treatment of Anxiety Disorders?

N Pitsikas - Molecules, 2024 - mdpi.com
Close to 19% of the world population suffers from anxiety. Current medications for this
chronic mental disorder have improved treatment over the last half century or more, but the …

Cell-type diversity in the bed nucleus of the stria terminalis to regulate motivated behaviors

MM Ortiz-Juza, RA Alghorazi… - Behavioural brain …, 2021 - Elsevier
Over the past few decades, the bed nucleus of the stria terminalis (BNST) gained popularity
as a unique brain region involved in regulating motivated behaviors related to …

Bed nucleus of the stria terminalis CB1 receptors and the FAAH enzyme modulate anxiety behavior depending on previous stress exposure

AB Borges-Assis, DL Uliana, SC Hott… - Progress in Neuro …, 2023 - Elsevier
The endocannabinoid (eCB) anandamide (AEA) is synthesized on-demand in the post-
synaptic terminal and can act on presynaptic cannabinoid type 1 (CB1) receptors …

NMDA receptors in the CeA and BNST differentially regulate fear conditioning to predictable and unpredictable threats

RL Ressler, TD Goode, C Evemy, S Maren - Neurobiology of learning and …, 2020 - Elsevier
Considerable work demonstrates that Pavlovian fear conditioning depends on N-methyl-D-
aspartate (NMDA) receptor-dependent plasticity within the amygdala. In addition, the bed …

The role of the bed nucleus of the stria terminalis in pain-induced aversive motivation

M Minami - Current Opinion in Behavioral Sciences, 2019 - Elsevier
Highlights•Opposing roles of CRF and NPY within the dlBNST in pain-induced aversive
responses.•Intra-vBNST glutamatergic transmission in pain-induced aversive …

Activation of the NMDA receptor–neuronal nitric oxide synthase pathway within the ventral bed nucleus of the stria terminalis mediates the negative affective …

S Deyama, Y Sugano, S Mori, T Amano, M Yoshioka… - …, 2017 - Elsevier
Pain consists of sensory and affective components. Although the neuronal mechanisms
underlying the sensory component of pain have been studied extensively, those underlying …

Chlorpyrifos intermittent exposure enhances cardiovascular but not behavioural responses to contextual fear conditioning in adult rats: Possible involvement of brain …

YFP Rosa, GG Noé, MGO Merlo, RR Calixto… - Behavioural Brain …, 2025 - Elsevier
Exposure to organophosphorus compounds (OPs) may cause psychiatric, neurologic,
biochemical, and cardiovascular abnormalities. Neurotoxicity of OP compounds is primarily …