The human lens grows by a process of epithelial cell division at its equator and the formation
of generations of differentiated fibre cells. Despite the process of continuous remodelling …

Aquaporin 0 (AQP0) was originally characterized as a membrane intrinsic protein,
specifically expressed in the lens fibers of the ocular lens and designated MIP, for major …

A novel Mr 28,000 erythrocyte transmembrane protein was recently purified and found to
exist in two forms,“28kDa” and “gly28kDa,” the latter containing N-linked carbohydrate …

Pannexins are homologous to innexins, the invertebrate gap junction family. However,
mammalian pannexin1 does not form canonical gap junctions, instead forming hexameric …

In this paper we compare the water-transport properties of Aquaporin (AQP1), a known
water channel, and those of the 28 kD Major Intrinsic Protein of Lens (MIP), a protein with an …

The structural organization and protein composition of lens fiber junctions isolated from adult
bovine and calf lenses were studied using combined electron microscopy …

MIP has been hypothesized to be a gap junction protein, a membrane ion channel, a
membrane water channel and a facilitator of glycerol transport and metabolism. These …

The lens major intrinsic protein (MIP, AQP0) is known to function as a water and solute
channel. However, MIP has also been reported to occur in close membrane contacts …

Detergent-solubilized plasma membrane protein of either adult bovine or calf lens and high-
performance liquid chromatography-purified major intrinsic protein (MIP) of the lens were …

The lens of the vertebrate eye is an astonishing organ, crystal-clear and perfectly shaped to
focus the incoming light onto the retina. Its physical appearance is totally unlike that of any …