RJ Cheng, AJ Xiong, YH Li, SY Pan… - Frontiers in cell and …, 2019 - frontiersin.org
Mesenchymal stem cells (MSCs) have a potently immunosuppressive capacity in both innate and adaptive immune responses. Consequently, MSCs transplantation has emerged …
Importance High-dose immunosuppressive therapy and autologous hematopoietic stem cell transplantation (HSCT) have shown efficacy in systemic sclerosis in phase 1 and small …
HL Atkins, M Bowman, D Allan, G Anstee, DL Arnold… - The Lancet, 2016 - thelancet.com
Background Strong immunosuppression, including chemotherapy and immune-depleting antibodies followed by autologous haemopoietic stem-cell transplantation (aHSCT), has …
J Liang, H Zhang, W Kong, W Deng, D Wang… - Stem Cell Research & …, 2018 - Springer
Objective The aim of this study was to evaluate the safety of mesenchymal stem cell infusion in patients with autoimmune diseases. Methods A total of 404 patients with autoimmune …
A Bryant, H Atkins, CE Pringle, D Allan… - JAMA …, 2016 - jamanetwork.com
Importance Some patients with myasthenia gravis (MG) do not respond to conventional treatment and have severe or life-threatening symptoms. Alternate and emerging therapies …
HL Atkins, MS Freedman - Neurotherapeutics, 2013 - Elsevier
Reports from more than 600 hematopoietic stem cell transplants (HSCT) have appeared in the medical literature for the last 1 and one-half decades. The patient's own stem cells are …
Systemic sclerosis is a progressive inflammatory disease that is frequently fatal and has limited treatment options. High-dose chemotherapy with autologous hematopoietic cell …
J Das, B Sharrack, JA Snowden - Current Hematologic Malignancy …, 2019 - Springer
Abstract Purpose of Review We summarise the current development of autologous haematopoietic stem cell transplantation (AHSCT) in treating multiple sclerosis (MS) and …
AW Loren, S Senapati - Blood, The Journal of the American …, 2019 - ashpublications.org
Patients with hematologic malignancies and those undergoing hematopoietic cell transplantation (HCT) face a complex set of challenges when considering options for fertility …