Chemotherapy resistance is a huge barrier for head and neck cancer (HNC) patients and
therefore requires close attention to understand its underlay mechanisms for effective …

Accumulated evidence indicates that immune cell populations play pivotal roles in the
process of tumor initiation, progression, recurrence, metastasis, and immune escape …

Immunotherapy has become one of the most promising approaches in tumor therapy, and
there are numerous associated clinical trials in China. As an immunosuppressive tumor …

Purpose Among oral squamous cell carcinoma (OSCC) patients who receive docetaxel,
cisplatin, and 5-fluorouracil (TPF) induction chemotherapy, those with a favorable …

Simple Summary There are no randomized studies comparing organ-preservation protocols
with chemo-selection to the classical total laryngectomy plus (chemo) radiotherapy. Thus …

Dendritic cells (DCs) are the most specialized antigen-presenting cells, and lymph nodes
(LNs) play an important role in the DC-mediated T-cell response. We evaluated the …

We employed a mechanistic learning approach, integrating on‐treatment tumor kinetics (TK)
modeling with various machine learning (ML) models to address the challenge of predicting …

Cisplatin is commonly used for the chemotherapy of tongue squamous cell carcinoma
(TSCC); however, adverse side effects and drug resistance impact its therapeutic efficacy …

Background: Induction chemotherapy (ICT) has become an initial treatment for head and
neck squamous cell carcinoma (HNSCC). However, myelosuppression, an unavoidable …

In view of the inherent limitations associated with performing dynamic contrast enhanced‐
magnetic resonance imaging (DCE‐MRI) in clinical settings, current study was designed to …